Affinity DataKi: 1.32E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
Affinity DataKi: 9.50E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+5nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.01nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.03nMAssay Description:Displacement of [3H]dynorphin from human kappa opioid receptor expressed in C6 giloma cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institute Of Chemical Biology
Curated by ChEMBL
Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.99nMAssay Description:Displacement of [3H]dynorphin from human kappa opioid receptor expressed in C6 giloma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.12E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.41E+5nMAssay Description:Inhibition of RNase A by precipitation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 525nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 692nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 263nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 724nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 1.35E+3nMAssay Description:Agonist activity at rat FFA3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 5.75E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 3.02E+4nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 5.37E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 3.89E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 1.32E+5nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 3.63E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 372nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 6.76E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 4.17E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 4.57E+4nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 245nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 1.78E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 251nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 1.17E+4nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 692nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 589nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 457nMAssay Description:Agonist activity at rat FFA3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.55E+4nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 4.57E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 1.82E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 525nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 708nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 288nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 6.17E+4nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 1.95E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
Affinity DataEC50: 537nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 617nMAssay Description:Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of...More data for this Ligand-Target Pair
Affinity DataEC50: 3.72E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...More data for this Ligand-Target Pair
Affinity DataEC50: 1.35E+3nMAssay Description:Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair