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Found 301 with Last Name = 'duvey' and Initial = 'g'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492703(CHEMBL2408158)
Affinity DataIC50:  53nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492718(CHEMBL2408008)
Affinity DataIC50:  60nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50051408(CHEMBL3337527 | US11071729, Compound 2)
Affinity DataIC50:  68nMAssay Description:Displacement of [3H]19 from human mGlu2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492724(CHEMBL2408176)
Affinity DataIC50:  77nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492705(CHEMBL2408007)
Affinity DataIC50:  90nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492726(CHEMBL2408161)
Affinity DataIC50:  108nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492704(CHEMBL2408152)
Affinity DataIC50:  262nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492721(CHEMBL2408183)
Affinity DataIC50:  316nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492733(CHEMBL2408193)
Affinity DataIC50:  364nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Addex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50492720(CHEMBL2408157)
Affinity DataIC50:  390nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565069(US11414395, Example 118)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565070(US11414395, Example 119)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565073(US11414395, Example 122)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565074(US11414395, Example 124)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565075(US11414395, Example 125)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565076(US11414395, Example 126)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565077(US11414395, Example 127)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565078(US11414395, Example 128)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565080(US11414395, Example 130)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565081(US11414395, Example 131)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565082(US11414395, Example 132)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565084(US11414395, Example 134)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565087(US11414395, Example 137)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565089(US11414395, Example 139)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM564997(US11414395, Example 45)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM564998(US11414395, Example 46)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM564999(US11414395, Example 47)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565001(US11414395, Example 49)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565002(US11414395, Example 50)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565003(US11414395, Example 51)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565004(US11414395, Example 52)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565005(US11414395, Example 53)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565006(US11414395, Example 54)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565007(US11414395, Example 55)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565008(US11414395, Example 56)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565009(US11414395, Example 57)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565010(US11414395, Example 58)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565011(US11414395, Example 59)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565012(US11414395, Example 60)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565013(US11414395, Example 61)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565017(US11414395, Example 66)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565020(US11414395, Example 69)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565023(US11414395, Example 72)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565025(US11414395, Example 74)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565026(US11414395, Example 75)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565027(US11414395, Example 76)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565028(US11414395, Example 77)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565029(US11414395, Example 78)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565030(US11414395, Example 79)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Pragma Therapeutics

US Patent
LigandPNGBDBM565031(US11414395, Example 80)
Affinity DataIC50: <500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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