Affinity DataKi: 11nMAssay Description:Antagonist activity at LPAR1/LPAR3 in rat glioma C62B cells assessed as inhibition of LPA-induced reduction in isoproterenol-stimulated [3H]cAMP accu...More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Competitive antagonist activity at N-terminal 3XHA-tagged human LPA3 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]G...More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Competitive antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liq...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Inhibition of autotoxin assessed as choline release from LPC using lysophosphatidylcholine as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 95nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 99nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:Competitive antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liq...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 187nMAssay Description:Inhibition of autotoxin assessed as choline release from LPC using lysophosphatidylcholine as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 367nMAssay Description:Inhibition of autotoxin assessed as choline release from LPC using lysophosphatidylcholine as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 512nMAssay Description:Competitive antagonist activity at N-terminal 3XHA-tagged human LPA3 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]G...More data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of SPHK1More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 4.40E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Virginia
Curated by ChEMBL
University Of Virginia
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.30E+3nMAssay Description:Inhibition of mouse recombinant SPHK2 expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair