Compile Data Set for Download or QSAR
maximum 50k data
Found 713 with Last Name = 'east' and Initial = 'sp'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50234380(CHEMBL245876 | quinolin-8-yl 4-methyl-3-(piperidin...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50234380(CHEMBL245876 | quinolin-8-yl 4-methyl-3-(piperidin...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121445((S)-2-Mercaptomethyl-hexanoic acid [(S)-5-amino-1-...)
Affinity DataKi:  19nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Fe of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121442(5-Guanidino-2-(2-mercaptomethyl-hexanoylamino)-pen...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144510(US8969568, 63)
Affinity DataIC50: <0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140322(US8912173, 48)
Affinity DataIC50:  0.100nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144560(US8969568, 113)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144559(US8969568, 112)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144555(US8969568, 108)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144541(US8969568, 94)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140393(US8912173, 118)
Affinity DataIC50:  0.100nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144532(US8969568, 85)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144516(US8969568, 69)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144512(US8969568, 65)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140394(US8912173, 119)
Affinity DataIC50:  0.100nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140337(US8912173, 63)
Affinity DataIC50:  0.100nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144493(US8969568, 45)
Affinity DataIC50:  0.100nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140321(US8912173, 47)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140361(US8912173, 86)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144518(US8969568, 71)
Affinity DataIC50:  0.200nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140342(US8912173, 68)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140360(US10947243, Example 85 | US8912173, 85 | US9914735...)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144483(US8969568, 35)
Affinity DataIC50:  0.200nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140353(US8912173, 78)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144529(US8969568, 82)
Affinity DataIC50:  0.200nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144573(US8969568, 126)
Affinity DataIC50:  0.200nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140380(US10947243, Example 105 | US8912173, 105 | US99147...)
Affinity DataIC50:  0.200nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144489(US8969568, 41)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140303(US8912173, 29)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140363(US8912173, 88)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140343(US8912173, 69)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140317(US8912173, 43)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140329(US8912173, 55)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140369(US10947243, Example 94 | US8912173, 94 | US9914735...)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144539(US8969568, 92)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144530(US8969568, 83)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144519(US8969568, 72)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140315(US8912173, 41)
Affinity DataIC50:  0.300nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144494(US8969568, 46)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144568(US8969568, 121)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144514(US8969568, 67)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140336(US8912173, 62)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140284(US8912173, 10)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140308(US8912173, 34)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140276(US8912173, 2)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140275(US8912173, 1)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140384(US10947243, Example 109 | US8912173, 109 | US99147...)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140376(US10947243, Example 101 | US8912173, 101 | US99147...)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM140368(US8912173, 93)
Affinity DataIC50:  0.400nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50137332((R)-2-Cyclopentylmethyl-N-[(S)-1-(4,5-difluoro-2-m...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against Escherichia coli peptide deformylase (PDF) Nickel containing enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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