Affinity DataKi: 674nMAssay Description:Antagonist activity at DP1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 873nMAssay Description:Antagonist activity at DP1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at DP1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of ADP-mediated human gel filtered platelet aggregation.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of PDE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV1 recombinant integrase catalyzed strand transfer activityMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of platelet aggregation as the concentration necessary to inhibit the change in light .More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 recombinant integrase catalyzed strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 recombinant integrase catalyzed strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 recombinant integrase catalyzed strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 recombinant integrase catalyzed strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of ADP-mediated human gel filtered platelet aggregation.More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of phsophorylated TrkA (unknown origin) assessed as inhibition of fluorescently-labelled substrate phosphorylation by CALIPER enzymatic as...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at DP1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of phsophorylated TrkA (unknown origin) assessed as inhibition of fluorescently-labelled substrate phosphorylation by CALIPER enzymatic as...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HIV1 recombinant integrase catalyzed strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity using immobilized DNA substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Competition with [1251]L-692,884 for binding to purified alpha IIb/beta3 integrin, activated by coating onto yttrium silicate scintillation proximity...More data for this Ligand-Target Pair