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Found 181 with Last Name = 'el-messery' and Initial = 'sm'
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448052(CHEMBL3115740)
Affinity DataIC50:  4nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  8nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  8nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196309(CHEMBL3929338)
Affinity DataIC50:  10nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM226165(N'-[4-Methoxybenzylidene-2-(6-chloro)-3-(4-met...)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196287(CHEMBL3936506)
Affinity DataIC50:  20nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50438444(CHEMBL2414370)
Affinity DataIC50:  30nMAssay Description:Inhibition of bovine liver DHFR measured every 1 min for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448057(CHEMBL3115735)
Affinity DataIC50:  60nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  80nMAssay Description:Inhibition of bovine liver DHFR measured every 1 min for 10 minsMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  80nMAssay Description:Inhibition of bovine DHFR after 2 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  80nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  80nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448056(CHEMBL3115736)
Affinity DataIC50:  90nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196313(CHEMBL3914501)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448067(CHEMBL3115730)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50058706(CHEMBL3326813)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448050(CHEMBL3115742)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448053(CHEMBL3115739)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196279(CHEMBL3946592)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196285(CHEMBL3932469)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196288(CHEMBL3959539)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50432816(CHEMBL2376081)
Affinity DataIC50:  300nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50432816(CHEMBL2376081)
Affinity DataIC50:  300nMAssay Description:Inhibition of bovine DHFR after 2 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448059(CHEMBL3115733)
Affinity DataIC50:  300nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196294(CHEMBL3947042)
Affinity DataIC50:  300nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50058696(CHEMBL3326818)
Affinity DataIC50:  400nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM226173(6-Chloro-2-((5-(4-chlorophenylamino)-1,3,4-thiadia...)
Affinity DataIC50:  400nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50432810(CHEMBL2376069)
Affinity DataIC50:  500nMAssay Description:Inhibition of bovine DHFR after 2 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448066(CHEMBL3115731)
Affinity DataIC50:  500nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50432810(CHEMBL2376069)
Affinity DataIC50:  500nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50448058(CHEMBL3115734)
Affinity DataIC50:  600nMAssay Description:Inhibition of bovine liver DHFR measured for every 1 min of 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50058709(CHEMBL3326823)
Affinity DataIC50:  600nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196306(CHEMBL3973809)
Affinity DataIC50:  600nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM226170(1-[2-(6,7-Dimethoxy)-3-(4-methoxy-phenyl)-4-oxo-3,...)
Affinity DataIC50:  600nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50542247(CHEMBL4647325)
Affinity DataIC50:  690nMAssay Description:Inhibition of human EGFR-TK using PTK substrate after 40 mins in presence of ATP by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50058705(CHEMBL3326812)
Affinity DataIC50:  700nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196283(CHEMBL3942503)
Affinity DataIC50:  700nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50542243(CHEMBL4649213)
Affinity DataIC50:  740nMAssay Description:Inhibition of human EGFR-TK using PTK substrate after 40 mins in presence of ATP by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196301(CHEMBL3919828)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196298(CHEMBL3965080)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196310(CHEMBL3945396)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196293(CHEMBL3944367)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50432814(CHEMBL2376066)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine DHFR after 2 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196282(CHEMBL3920434)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM226163(2-[(6,7-Dimethoxy)-3-(4-methoxyphenyl)-4-oxo-3,4-d...)
Affinity DataIC50:  800nMpH: 7.4 T: 2°CAssay Description:The assay mixture contained 50 μM Tris-HCl buffer (pH 7.4), 50 μM NADPH, 10 μl DMSO or the same volume of DMSO solution containing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50432814(CHEMBL2376066)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50058704(CHEMBL3326816)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine liver DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196319(CHEMBL3910321)
Affinity DataIC50:  900nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196304(CHEMBL3959977)
Affinity DataIC50:  900nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
Future University

Curated by ChEMBL
LigandPNGBDBM50196307(CHEMBL3928739)
Affinity DataIC50:  900nMAssay Description:Inhibition of bovine liver DHFR preincubated for 2 mins followed by addition of FH2 as substrate and NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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