Compile Data Set for Download or QSAR
maximum 50k data
Found 554 with Last Name = 'ellston' and Initial = 'rp'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183849((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50: <1nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM7647(4-[(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidi...)
Affinity DataIC50: <3nMpH: 7.0 T: 2°CAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183837((R)-1-((4-(3-chloro-4-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM7649(2,4-bisanilinopyrimidine deriv. 9 | 4-({4-[(2-fluo...)
Affinity DataIC50:  6nMpH: 7.0 T: 2°CAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183856(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183856(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183837((R)-1-((4-(3-chloro-4-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183864((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183862((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183864((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183862((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183858(4-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183835((R)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183840(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183835((R)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM7628(2,4-bis anilino pyrimidine deriv. 24 | 5-bromo-2-N...)
Affinity DataIC50:  10nMAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183850((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183857((2R,4R)-1-((4-(3-chloro-2-fluorophenylamino)-7-met...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183838((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183847(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  10nMAssay Description:Antiproliferative activity against EGF-stimulated human KB cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183853((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183850((R)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183857((2R,4R)-1-((4-(3-chloro-2-fluorophenylamino)-7-met...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183838((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183852(2-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183863((S)-1-((4-(3-chloro-4-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183863((S)-1-((4-(3-chloro-4-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183847(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183841(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183844((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183841(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183852(2-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183844((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183846(4-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  25nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183843((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183842((S)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183839(1-((4-(3-chloro-2-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183839(1-((4-(3-chloro-2-fluorophenylamino)-7-methoxyquin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183854((R)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183843((S)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183842((S)-1-((4-(3-chloro-2-fluorophenylamino)-7-methoxy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183854((R)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM7646(CHEMBL102926 | Imidazo[1,2-a]pyridine deriv. 6 | N...)
Affinity DataIC50:  32nMpH: 7.0 T: 2°CAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  33nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  33nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183840(3-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  35nMAssay Description:Antiproliferative activity against EGF-stimulated human KB cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM7645(4-{2-methylimidazo[1,2-a]pyridin-3-yl}-N-phenylpyr...)
Affinity DataIC50:  36nMpH: 7.0 T: 2°CAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183858(4-(((4-(3-chloro-2-fluorophenylamino)-7-methoxyqui...)
Affinity DataIC50:  40nMAssay Description:Antiproliferative activity against EGF-stimulated human KB cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183860((R)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  40nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50183860((R)-2-(((4-(3-chloro-2-fluorophenylamino)-7-methox...)
Affinity DataIC50:  40nMAssay Description:Inhibition of EGFR in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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