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Found 153 with Last Name = 'estiu' and Initial = 'g'
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKi:  21nM ΔG°:  -43.4kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22450(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)
Affinity DataKi:  28nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKi:  48nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22450(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)
Affinity DataKi:  88nM ΔG°:  -39.9kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50124161(CHEMBL168526 | N-benzylsulfamide)
Affinity DataKi:  120nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50124161(CHEMBL168526 | N-benzylsulfamide)
Affinity DataKi:  130nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataKi:  142nM ΔG°:  -38.7kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428808(CHEMBL229189 | N-(Cyclopropylsulfamoyl)Cyclopropan...)
Affinity DataKi:  160nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428814(CHEMBL229904)
Affinity DataKi:  170nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50124161(CHEMBL168526 | N-benzylsulfamide)
Affinity DataKi:  300nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428813(CHEMBL375030)
Affinity DataKi:  320nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428807(CHEMBL388325 | N-(Cyclohexylsulfamoyl)Cyclohexanam...)
Affinity DataKi:  320nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428812(BENZYL(BENZYLSULFAMOYL)AMINE | N,N''-Dibenzylsulfa...)
Affinity DataKi:  380nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428810(BUTYL(BUTYLSULFAMOYL)AMINE)
Affinity DataKi:  410nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428806(4-(Morpholinosulfonyl)Morpholine | 4-Morpholinosul...)
Affinity DataKi:  470nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428812(BENZYL(BENZYLSULFAMOYL)AMINE | N,N''-Dibenzylsulfa...)
Affinity DataKi:  650nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428810(BUTYL(BUTYLSULFAMOYL)AMINE)
Affinity DataKi:  690nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428817(CHEMBL2335232 | Hexyl Sulfamate)
Affinity DataKi:  700nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428807(CHEMBL388325 | N-(Cyclohexylsulfamoyl)Cyclohexanam...)
Affinity DataKi:  700nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428817(CHEMBL2335232 | Hexyl Sulfamate)
Affinity DataKi:  730nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428808(CHEMBL229189 | N-(Cyclopropylsulfamoyl)Cyclopropan...)
Affinity DataKi:  770nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428817(CHEMBL2335232 | Hexyl Sulfamate)
Affinity DataKi:  820nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50124161(CHEMBL168526 | N-benzylsulfamide)
Affinity DataKi:  840nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428816(2-Propylpentyl Sulfamate | CHEMBL2335233)
Affinity DataKi:  860nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428816(2-Propylpentyl Sulfamate | CHEMBL2335233)
Affinity DataKi:  890nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428814(CHEMBL229904)
Affinity DataKi:  890nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428813(CHEMBL375030)
Affinity DataKi:  910nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50124161(CHEMBL168526 | N-benzylsulfamide)
Affinity DataKi:  940nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataKi:  995nM ΔG°:  -33.9kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428816(2-Propylpentyl Sulfamate | CHEMBL2335233)
Affinity DataKi:  1.92E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKi:  2.00E+3nM ΔG°:  -32.2kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428817(CHEMBL2335232 | Hexyl Sulfamate)
Affinity DataKi:  2.82E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428816(2-Propylpentyl Sulfamate | CHEMBL2335233)
Affinity DataKi:  2.98E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428815(1-[Propyl(Sulfamoyl)Amino]Propane | CHEMBL229954 |...)
Affinity DataKi:  3.53E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428817(CHEMBL2335232 | Hexyl Sulfamate)
Affinity DataKi:  3.66E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428816(2-Propylpentyl Sulfamate | CHEMBL2335233)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428809(CHEMBL229740 | N,N''-Dipropylsulfamide)
Affinity DataKi:  4.69E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428797(CHEMBL2335234)
Affinity DataKi:  5.38E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428799(CHEMBL450699 | Methyl 2-(Tert-Butoxycarbonylsulfam...)
Affinity DataKi:  5.92E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22450(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)
Affinity DataKi:  6.10E+3nM ΔG°:  -29.5kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM22449(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Affinity DataKi:  6.30E+3nM ΔG°:  -29.4kJ/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428810(BUTYL(BUTYLSULFAMOYL)AMINE)
Affinity DataKi:  6.64E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428807(CHEMBL388325 | N-(Cyclohexylsulfamoyl)Cyclohexanam...)
Affinity DataKi:  6.64E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428813(CHEMBL375030)
Affinity DataKi:  6.88E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428815(1-[Propyl(Sulfamoyl)Amino]Propane | CHEMBL229954 |...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428802(CHEMBL501961)
Affinity DataKi:  7.66E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428801(CHEMBL471637)
Affinity DataKi:  7.97E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428798(CHEMBL511132)
Affinity DataKi:  8.09E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428800(CHEMBL199831 | Methyl 3-(Butylsulfamoylamino)Propa...)
Affinity DataKi:  8.37E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
National University Of La Plata

Curated by ChEMBL
LigandPNGBDBM50428803(CHEMBL461137)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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