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Found 375 with Last Name = 'faull' and Initial = 'a'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385474(CHEMBL2036748)
Affinity DataKi:  400nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human HEK cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364748(CHEMBL1952100)
Affinity DataIC50: <0.100nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364751(CHEMBL1951908)
Affinity DataIC50: <0.100nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364745(CHEMBL1951916)
Affinity DataIC50: <0.100nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185681((R)-N-ethyl-N-(1-(3-(3-fluorophenyl)-3-(4-(methyls...)
Affinity DataIC50:  0.220nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364743(CHEMBL1951914)
Affinity DataIC50:  0.260nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50:  0.320nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185666((R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50:  0.320nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364771(CHEMBL1951913)
Affinity DataIC50:  0.440nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364746(CHEMBL1951917)
Affinity DataIC50:  0.550nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364770(CHEMBL1951912)
Affinity DataIC50:  0.680nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364744(CHEMBL1951915)
Affinity DataIC50:  0.690nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364743(CHEMBL1951914)
Affinity DataIC50:  0.690nMAssay Description:Antagonist activity at CCR5 in allo T cells assessed as inhibition of MIP-1beta-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185673((S)-N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(...)
Affinity DataIC50:  0.760nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012922(4-Methyl-2-[(pyridin-2-ylmethyl)-amino]-pentanoic ...)
Affinity DataIC50:  1nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012922(4-Methyl-2-[(pyridin-2-ylmethyl)-amino]-pentanoic ...)
Affinity DataIC50:  1nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185670((R)-N-(1-(3-(3-chlorophenyl)-3-(4-(methylsulfonyl)...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185667((R)-N-(1-(3-(3-chloro-5-fluorophenyl)-3-(4-(methyl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364750(CHEMBL1951906)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364752(CHEMBL1951898)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012928(2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...)
Affinity DataIC50:  1.60nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012923(2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...)
Affinity DataIC50:  1.70nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012923(2-(3-Aminomethyl-benzylamino)-4-methyl-pentanoic a...)
Affinity DataIC50:  1.70nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50173389(CHEMBL198150 | N-Ethyl-2-(4-methanesulfonyl-phenyl...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012932(4-(1-{1-Cyclohexylmethyl-2-hydroxy-4-[2-(8-isobuty...)
Affinity DataIC50:  1.90nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364766(CHEMBL1951907)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364756(CHEMBL1951894)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364747(CHEMBL1951918)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385450(CHEMBL2036782)
Affinity DataIC50:  3.5nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012925(2-Amino-6-(1-{1-cyclohexylmethyl-2-hydroxy-4-[2-(8...)
Affinity DataIC50:  3.70nMAssay Description:Tested in vitro for their ability to inhibit human renin incubated with human angiotensinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364769(CHEMBL1951911)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364755(CHEMBL1951893)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385479(CHEMBL2036755)
Affinity DataIC50:  5nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385450(CHEMBL2036782)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of MCP1-induced CCR2-mediated chemotaxis in human THP-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364767(CHEMBL1949696)
Affinity DataIC50:  5.40nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385450(CHEMBL2036782)
Affinity DataIC50:  5.80nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364753(CHEMBL1951899)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364764(CHEMBL1951904)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385469(CHEMBL2036757)
Affinity DataIC50:  10nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036368((Z)-6-[2-(1,1-Dimethyl-2-phenyl-ethyl)-4-pyridin-3...)
Affinity DataIC50:  12nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50364759(CHEMBL1951897)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036355((Z)-6-{2-[1-(2-Cyano-4-fluoro-phenoxy)-1-methyl-et...)
Affinity DataIC50:  15nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385468(CHEMBL2036758)
Affinity DataIC50:  16nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385456(CHEMBL2036775)
Affinity DataIC50:  17nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010960((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)
Affinity DataIC50:  17nMAssay Description:In vitro Inhibition of thromboxane synthase from human blood platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385466(CHEMBL2036760)
Affinity DataIC50:  17nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50280074((Z)-6-{(2S,4S,5R)-2-[1-Methyl-1-(4-methyl-2-nitro-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50280066((Z)-6-{(2S,4S,5R)-2-[1-Methyl-1-(4-methyl-2-nitro-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50185676((R)-N-(1-(3-(2,3-difluorophenyl)-3-(4-(methylsulfo...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50288601((Z)-6-[(2S,4S,5R)-2-(4-Cyano-phenyl)-4-pyridin-3-y...)
Affinity DataIC50:  20nMAssay Description:Compound was tested for thromboxane TXA2 synthase inhibitory activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
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