TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 0.0100nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 2.60nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 3.30nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 4nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 6nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 8.60nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 9nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 9.10nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 9.40nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 9.70nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 9.90nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 10nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 10nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 11nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 12nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 12nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 13nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 16nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 18nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 20nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 22nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 27nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 30nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 31nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 31nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 63nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 70nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of Sprague-Dawley rat brain mitochondria MAOB by continuous spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 90nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia
US Patent
Fondazione Istituto Italiano Di Tecnologia
US Patent
Affinity DataIC50: 92nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 106nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair