Affinity DataIC50: 0.100nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based ...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma
Curated by ChEMBL
Leo Pharma
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of human recombinant PDE4D after 1 hr by SPA in presence of radioactively labeled cAMPMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of Escherichia coli DNA gyrase by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 261nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based ...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based ...More data for this Ligand-Target Pair
Affinity DataIC50: 305nMAssay Description:Human recombinant PDE4 (Gene bank accession no NM006203) was incubated for 1 hour with the test compound at concentrations up to 10 μM, with cAM...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based ...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based ...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity using pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence based ...More data for this Ligand-Target Pair