Compile Data Set for Download or QSAR
maximum 50k data
Found 493 with Last Name = 'finn' and Initial = 'p'
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403((3,5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)pheno...)
Affinity DataKi:  2.17nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM18869(2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataKi:  7.18nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242403((3,5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)pheno...)
Affinity DataKi:  35.2nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50100887(CHEMBL3325857)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Plasmodium falciparum SUB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50100888(CHEMBL1873576)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of Plasmodium falciparum SUB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242404((4S)-4-(3-chlorophenyl)-2-[(3,5-dimethyl-4-(4-hydr...)
Affinity DataKi:  1.25E+4nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50242404((4S)-4-(3-chlorophenyl)-2-[(3,5-dimethyl-4-(4-hydr...)
Affinity DataKi:  1.46E+4nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor beta (unknown origin) expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361211(CHEMBL1934340)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353049(CHEMBL1822511)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361213(CHEMBL1934342)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361210(CHEMBL1934339)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361212(CHEMBL1934341)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356075(CHEMBL1911818)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361214(CHEMBL1934343)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361206(CHEMBL1934335)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361208(CHEMBL1934337)
Affinity DataIC50:  0.640nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361209(CHEMBL1934338)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356076(CHEMBL1911817)
Affinity DataIC50:  1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356075(CHEMBL1911818)
Affinity DataIC50:  1nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356078(CHEMBL1911815)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356076(CHEMBL1911817)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356091(CHEMBL1911679)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356090(CHEMBL1911678)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS activity in human A549 cells assessed as amount of GM1 on the cell membrane after 72 hrs by FL-CTB-based fluorescent microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356090(CHEMBL1911678)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356091(CHEMBL1911679)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394820(CHEMBL2163829)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394812(CHEMBL2163838)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394804(CHEMBL2163828)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394807(CHEMBL2163825)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS in human A549 cells assessed as decrease in GM1 synthesis after 72 hrs by Fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361207(CHEMBL1934336)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356077(CHEMBL1911816)
Affinity DataIC50:  2nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361215(CHEMBL1934344)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361204(CHEMBL1934353)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268097(6-{[2-(9H-Fluoren-9-yliden)acetyl]amino}-N-hydroxy...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361204(CHEMBL1934353)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394809(CHEMBL2163823)
Affinity DataIC50:  3nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 493 total ) | Next | Last >>
Jump to: