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Found 32 with Last Name = 'fisher' and Initial = 'jf'
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82122(Vinylsulfone, 7)
Affinity DataKi:  0.530nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50368890(CHEMBL1790792)
Affinity DataKi:  4nMAssay Description:In vitro inhibitory activity against biotinylated human HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50368891(CHEMBL1790796)
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity against biotinylated human HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50368893(CHEMBL1790794)
Affinity DataKi:  20nMAssay Description:In vitro inhibitory activity against biotinylated human HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50368889(CHEMBL1790790)
Affinity DataKi:  45nMAssay Description:In vitro inhibitory activity against biotinylated human HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50368892(CHEMBL1790797)
Affinity DataKi:  53nMAssay Description:In vitro inhibitory activity against biotinylated human HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  64nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50368887(CHEMBL1790791)
Affinity DataKi: >100nMAssay Description:In vitro inhibitory activity against biotinylated human HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50368888(CHEMBL1790793)
Affinity DataKi:  130nMAssay Description:In vitro inhibitory activity against biotinylated human HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase(Pseudomonas aeruginosa)
TBA

Curated by ChEMBL
LigandPNGBDBM50386412(CHEMBL2047302)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa PAO1 NagZ using PNP-GlcNAc as substrate assessed as release of 4-nitrophenolate ion after 4 mins by ...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  320nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82121(Gama, gama-dimethyl derivative, 6)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82119(Sulfoxide, 4)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase(Pseudomonas aeruginosa)
TBA

Curated by ChEMBL
LigandPNGBDBM50386415(CHEMBL2047305)
Affinity DataKi:  3.30E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa PAO1 NagZ using PNP-GlcNAc as substrate assessed as release of 4-nitrophenolate ion after 4 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase(Pseudomonas aeruginosa)
TBA

Curated by ChEMBL
LigandPNGBDBM50386414(CHEMBL2047304)
Affinity DataKi:  3.50E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa PAO1 NagZ using PNP-GlcNAc as substrate assessed as release of 4-nitrophenolate ion after 4 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82120(Alpha, alpha-dimethyl derivative, 5)
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase(Pseudomonas aeruginosa)
TBA

Curated by ChEMBL
LigandPNGBDBM50386413(CHEMBL2047303)
Affinity DataKi:  5.10E+4nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa PAO1 NagZ using PNP-GlcNAc as substrate assessed as release of 4-nitrophenolate ion after 4 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50482776(CHEBI:70718 | Ceftaroline Fosamil | PPI-0903 | TAK...)
Affinity DataIC50:  49.7nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50482776(CHEBI:70718 | Ceftaroline Fosamil | PPI-0903 | TAK...)
Affinity DataIC50:  71.6nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50483327(CEFTOBIPROLE MEDOCARIL)
Affinity DataIC50:  72.4nMAssay Description:Inhibition of methicillin-susceptible Staphylococcus aureus ATCC 29213 PBP 3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPutative penicillin-binding protein 2B(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50483327(CEFTOBIPROLE MEDOCARIL)
Affinity DataIC50:  144nMAssay Description:Inhibition of methicillin-susceptible Staphylococcus aureus ATCC 29213 PBP 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPutative penicillin-binding protein 2B(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50482776(CHEBI:70718 | Ceftaroline Fosamil | PPI-0903 | TAK...)
Affinity DataIC50:  146nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50482776(CHEBI:70718 | Ceftaroline Fosamil | PPI-0903 | TAK...)
Affinity DataIC50:  233nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus PBP 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50483328(CHEMBL387640 | ME1036)
Affinity DataIC50:  262nMAssay Description:Binding affinity to methicillin-resistant Staphylococcus aureus MF535HR PBP 2a by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50483327(CEFTOBIPROLE MEDOCARIL)
Affinity DataIC50:  723nMAssay Description:Inhibition of methicillin-susceptible Staphylococcus aureus ATCC 29213 PBP 2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50483327(CEFTOBIPROLE MEDOCARIL)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus OC 3726 PBP 2aMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 4(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50483327(CEFTOBIPROLE MEDOCARIL)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of methicillin-susceptible Staphylococcus aureus ATCC 29213 PBP 4More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 4(Staphylococcus aureus)
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50482776(CHEBI:70718 | Ceftaroline Fosamil | PPI-0903 | TAK...)
Affinity DataIC50: >1.46E+3nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound lytic murein transglycosylase B(Escherichia coli (strain K12))
TBA

Curated by ChEMBL
LigandPNGBDBM50386415(CHEMBL2047305)
Affinity DataKd:  1.01E+6nMAssay Description:Binding affinity to Escherichia coli K12 MG1655 His6x-tagged MltB lytic transglycosylase assessed as intrinsic fluorescence of tryptophan and/or tyro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound lytic murein transglycosylase B(Escherichia coli (strain K12))
TBA

Curated by ChEMBL
LigandPNGBDBM50386413(CHEMBL2047303)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to Escherichia coli K12 MG1655 His6x-tagged MltB lytic transglycosylase assessed as intrinsic fluorescence of tryptophan and/or tyro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound lytic murein transglycosylase B(Escherichia coli (strain K12))
TBA

Curated by ChEMBL
LigandPNGBDBM50386414(CHEMBL2047304)
Affinity DataKd:  1.89E+5nMAssay Description:Binding affinity to Escherichia coli K12 MG1655 His6x-tagged MltB lytic transglycosylase assessed as intrinsic fluorescence of tryptophan and/or tyro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane-bound lytic murein transglycosylase B(Escherichia coli (strain K12))
TBA

Curated by ChEMBL
LigandPNGBDBM50386412(CHEMBL2047302)
Affinity DataKd:  1.74E+5nMAssay Description:Binding affinity to Escherichia coli K12 MG1655 His6x-tagged MltB lytic transglycosylase assessed as intrinsic fluorescence of tryptophan and/or tyro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed