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Found 340 with Last Name = 'flaherty' and Initial = 'dp'
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405890(CHEMBL4782535)
Affinity DataKi:  0.320nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405889(CHEMBL4741159)
Affinity DataKi:  8.10nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  13nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  16nMAssay Description:Inhibition of human carbonic anhydrase 13 expressed in Escherichia coliBL21(DE3) pLysS incubated for 10 mins by phenol red dye based assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50547697(CHEMBL4739913)
Affinity DataKi:  20nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405887(CHEMBL4750765)
Affinity DataKi:  25nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM16669(CHEMBL281376 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-y...)
Affinity DataKi:  29nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405888(CHEMBL5280695)
Affinity DataKi:  38nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405885(CHEMBL4749585)
Affinity DataKi:  47nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM10868(1,3,4-Thiadiazole-2-sulfonamide, 6 | 1,3,4-thiadia...)
Affinity DataKi:  60nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405886(CHEMBL4753745)
Affinity DataKi:  78nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604204(CHEMBL5188949)
Affinity DataKi:  900nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) assessed as displacement of radioligand at 10 uM by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604193(CHEMBL5187824)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) assessed as displacement of radioligand at 10 uM by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050546(CHEMBL3182699)
Affinity DataIC50:  1nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050547(CHEMBL3182449)
Affinity DataIC50:  2nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050542(CHEMBL3183497)
Affinity DataIC50:  2nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50312125(3-chloro-N-(3-(3-methylbenzamido)phenyl)benzamide ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050541(CHEMBL3188749)
Affinity DataIC50:  4nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50:  4nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050538(CHEMBL3182091)
Affinity DataIC50:  5nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050544(CHEMBL3187764)
Affinity DataIC50:  7nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50123519(2'-{[2-(4-Methoxy-phenyl)-acetylamino]-methyl}-bip...)
Affinity DataIC50:  7nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050503(CHEMBL3187482)
Affinity DataIC50:  9nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050540(CHEMBL3182359)
Affinity DataIC50:  10nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050534(CHEMBL3183773)
Affinity DataIC50:  10nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050547(CHEMBL3182449)
Affinity DataIC50:  10nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050503(CHEMBL3187482)
Affinity DataIC50:  11nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050545(CHEMBL3186000)
Affinity DataIC50:  11nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050530(CHEMBL3188857)
Affinity DataIC50:  14nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50312105(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Affinity DataIC50:  16nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050433(CHEMBL3186489)
Affinity DataIC50:  21nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050508(CHEMBL3186695)
Affinity DataIC50:  23nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050522(CHEMBL3182551)
Affinity DataIC50:  25nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050157(CHEMBL1310568)
Affinity DataIC50:  27nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050451(CHEMBL3182777)
Affinity DataIC50:  29nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050504(CHEMBL3182725)
Affinity DataIC50:  29nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050495(CHEMBL3185736)
Affinity DataIC50:  30nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050540(CHEMBL3182359)
Affinity DataIC50:  30nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050498(CHEMBL3187806)
Affinity DataIC50:  31nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050447(CHEMBL1716797)
Affinity DataIC50:  37nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050503(CHEMBL3187482)
Affinity DataIC50:  38nMAssay Description:Inhibition of TASK-3 (unknown origin) expressed in HEK293 cells by QPatch assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050437(CHEMBL1532914)
Affinity DataIC50:  45nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050440(CHEMBL3184966)
Affinity DataIC50:  52nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050504(CHEMBL3182725)
Affinity DataIC50:  60nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050542(CHEMBL3183497)
Affinity DataIC50:  66nMAssay Description:Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050543(CHEMBL1480257)
Affinity DataIC50:  73nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050157(CHEMBL1310568)
Affinity DataIC50:  75nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050493(CHEMBL3184095)
Affinity DataIC50:  79nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050453(CHEMBL3182370)
Affinity DataIC50:  86nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50050494(CHEMBL3181939)
Affinity DataIC50:  91nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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