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Found 88 with Last Name = 'foley' and Initial = 'lh'
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099120(5-(2-Hydroxy-ethyl)-5-(4-phenoxy-phenyl)-pyrimidin...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50:  65nMAssay Description:Inhibition of collagenase-3, Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  78nMAssay Description:Inhibition of collagenase-3, Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50:  81nMAssay Description:Inhibition of human neutrophil collagenase-I, Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50:  81nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099120(5-(2-Hydroxy-ethyl)-5-(4-phenoxy-phenyl)-pyrimidin...)
Affinity DataIC50:  118nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human neutrophil collagenase-I, Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50:  164nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214016(CHEMBL243342 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214007(CHEMBL394621 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214001(CHEMBL389494 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50:  330nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214008(CHEMBL243343 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214003(CHEMBL243134 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214000(CHEMBL243180 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  450nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50:  530nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214004(CHEMBL243116 | N-(4-((1-(2-fluorobenzyl)-3-butyl-2...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214014(CHEMBL245018 | N-(4-((1-(2-fluorobenzyl)-3-butyl-2...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214010(CHEMBL244165 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  690nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50:  696nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214012(CHEMBL394368 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  790nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099116(5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50:  863nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099116(5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50:  868nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50:  898nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50:  930nMAssay Description:Inhibition of Stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214009(3-(cyclopropylmethyl)-8-({4-[(dimethylsulfamoyl)am...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214002(CHEMBL244590 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214015(1-(2-fluorobenzyl)-8-(4-aminobenzyl)-3-(cyclopropy...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214006(CHEMBL397513 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphoenolpyruvate carboxykinase, cytosolic [GTP](Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50214013(CHEMBL242486 | N-(4-((1-(2-fluorobenzyl)-3-(cyclop...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of human cPEPCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099117(5-Methyl-5-(4-octyloxy-benzyl)-pyrimidine-2,4,6-tr...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099119(5-Biphenyl-4-yl-5-ethyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099124(1,5-Dimethyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099120(5-(2-Hydroxy-ethyl)-5-(4-phenoxy-phenyl)-pyrimidin...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099125(5-Hexyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL1...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099118(5-methyl-5-(4-phenoxyphenyl)barbituric acid | CHEM...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099121(5-Benzyloxymethyl-5-(4-phenoxy-phenyl)-pyrimidine-...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099122(5-Biphenyl-4-yl-5-hexyl-2-thioxo-dihydro-pyrimidin...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099116(5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | ...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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