Affinity DataIC50: 4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of MCP-1 in LPS-stimulated human whole blood incubate for 24 hrs by immuno assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair