Compile Data Set for Download or QSAR
maximum 50k data
Found 1312 with Last Name = 'franco' and Initial = 'l'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM18372((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethan...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50139181((1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotet...)
Affinity DataKi:  2.60nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50160720(3-hydroxy-3-methylglutaric acid | 3-hydroxy-3-meth...)
Affinity DataKi:  23.5nMAssay Description:Inhibitory constant against HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataKi:  3.40E+3nMAssay Description:Mixed type inhibition of human recombinant PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataKi:  6.00E+3nMAssay Description:Mixed type inhibition of human recombinant PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50385306(CHEMBL2002784)
Affinity DataKi:  6.20E+3nMAssay Description:Mixed-type inhibition of human recombinant GST-tagged PTP1B expressed in Escherichia coli TB1 cells using p-NPP as substrate by double reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50241428(CHEMBL401612 | N-(6-Methyl-1,3-benzothiazol-2-yl)-...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 by double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50391854(CHEMBL463665)
Affinity DataKi:  7.10E+3nMAssay Description:Non-competitive inhibition of human recombinant PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50385307(CHEMBL2035961)
Affinity DataKi:  7.90E+3nMAssay Description:Mixed-type inhibition of human recombinant GST-tagged PTP1B expressed in Escherichia coli TB1 cells using p-NPP as substrate by double reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50385308(CHEMBL2035962)
Affinity DataKi:  7.90E+3nMAssay Description:Mixed-type inhibition of human recombinant GST-tagged PTP1B expressed in Escherichia coli TB1 cells using p-NPP as substrate by double reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM54263((4aS,6aR,6aR,6bR,8aR,12aR,14aS)-10-keto-2,2,6a,6b,...)
Affinity DataKi:  8.00E+3nMAssay Description:Mixed type inhibition of human recombinant PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidad Aut£Noma Del Estado De Morelos

Curated by ChEMBL
LigandPNGBDBM50241429(CHEMBL401525 | N-(6-Ethoxy-1,3-benzothiazol-2-yl)-...)
Affinity DataKi:  2.04E+4nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 by double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM50139181((1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotet...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibitory constant against HMG-CoA reductase with alpha asaroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Universidad Nacional AutóNoma De MéXico

Curated by ChEMBL
LigandPNGBDBM18372((3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethan...)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibitory constant against HMG-CoA reductase with alpha asaroneMore data for this Ligand-Target Pair
LigandPNGBDBM50512300(CHEMBL4575012)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50512313(CHEMBL4435694)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50184359((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards human melanocortin receptor (hMC1R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512302(CHEMBL4441262)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50212693(2-(4-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
Affinity DataIC50:  1.70nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50212693(2-(4-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
Affinity DataIC50:  1.70nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50184359((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards human melanocortin receptor (hMC4R) using NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512303(CHEMBL4582480)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227759(3-(4-(3-((6-chloro-1H-indole-2-carboxamido)methyl)...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227736(2-(4-(5-((2-fluoro-4-(trifluoromethyl)benzamido)me...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227745(2-(4-(3-((2-bromo-4-(trifluoromethyl)benzamido)met...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227743(2-methyl-2-(2-methyl-4-(3-((2-methyl-4-(trifluorom...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50199779(3-(4-((R)-3-(4-ethyl-2-(pyridin-2-yl)phenoxy)butox...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50199776(3-(2-ethyl-4-((R)-3-(4-ethyl-2-(pyridin-2-yl)pheno...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227746(3-(4-(3-((5-chloro-1H-indole-2-carboxamido)methyl)...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227761(2-(4-(3-fluoro-5-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227752(2-(4-(3-((2-chloro-4-(trifluoromethyl)benzamido)me...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227736(2-(4-(5-((2-fluoro-4-(trifluoromethyl)benzamido)me...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50199781(3-(2-ethyl-4-((R)-3-(2-(pyridin-2-yl)-4-(trifluoro...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50199778(3-(4-((R)-3-(4-ethyl-2-(thiazol-4-yl)phenoxy)butox...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50213330(2-(6-(4-((4-(trifluoromethyl)phenoxy)methyl)benzyl...)
Affinity DataIC50:  3.60nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50512301(CHEMBL4570812)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50126018(2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benz...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227741(2-(4-(3-((2-ethyl-4-(trifluoromethyl)benzamido)met...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50451759(CHEMBL2371219)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration of compound was determined against hMC4R through displacement of NDP-MSH radioligand using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227757(2-(4-(3-((2-fluoro-4-(trifluoromethyl)benzamido)me...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50194635((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM28691(5-methyl-2-({3-[(7-methyl-1H-indole-1-)sulfonyl]be...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM28674(2-({3-[(2-carboxy-4-chlorophenyl)carbamoyl]benzene...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50199777(3-(2-methyl-4-((R)-3-(2-(pyridin-2-yl)-4-(trifluor...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50194631((R)-3-{4-[3-(4-ethyl-2-phenoxy-phenoxy)-butoxy]-2-...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50227749(2-(4-(3-((2-methoxy-4-(trifluoromethyl)benzamido)m...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1312 total ) | Next | Last >>
Jump to: