TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Binding affinity to angiotensin converting enzyme 2More data for this Ligand-Target Pair
TargetDeoxyribonuclease-2-alpha(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to Dnase 2More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity to urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataKi: 6.70E+3nMAssay Description:Binding affinity to urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Binding affinity to ErbB-2More data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to tissue factor/factor 7aMore data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 3nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 8nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 13nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 15nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 16nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 18nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 19nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 23nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 24nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 26nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 30nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 31nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 33nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 41nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 43nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 58nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of Plasmodium falciparum ENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
Affinity DataIC50: 100nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli)
Rutgers, The State University of New Jersey
US Patent
Rutgers, The State University of New Jersey
US Patent
Affinity DataIC50: 140nMAssay Description:Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Jacobus Pharmaceutical
Curated by ChEMBL
Jacobus Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of PfENR enzymatic activityMore data for this Ligand-Target Pair
TargetCathepsin G(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair