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Found 122 with Last Name = 'fujino' and Initial = 'm'
TargetMelanin-concentrating hormone receptor 1(RAT)
Takeda Chemical Industries

Curated by PDSP Ki Database
LigandPNGBDBM50150715(4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethyla...)
Affinity DataKi:  8.60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataIC50:  0.0600nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataIC50:  0.0700nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50043326(CHEMBL438733 | c(Cys-Ser-Cys)-Ser-Ser-Leu-Met-Asp-...)
Affinity DataIC50:  0.0930nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataIC50:  0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50409694(CHEMBL2092994)
Affinity DataIC50:  0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50000558(CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...)
Affinity DataIC50:  0.120nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50000558(CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...)
Affinity DataIC50:  0.150nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50043322(CHEMBL427748 | c(Cys-Ser-c(Cys-Ser-Ser-Leu-Met-Asp...)
Affinity DataIC50:  0.170nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368776(CHEMBL1790962)
Affinity DataIC50:  0.170nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368773(CHEMBL1790959)
Affinity DataIC50:  0.180nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368774(CHEMBL1790963)
Affinity DataIC50:  0.190nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)
Affinity DataIC50:  0.200nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122660(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122659(CHEMBL20511 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368775(CHEMBL1790960)
Affinity DataIC50:  0.200nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122667(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368772(CHEMBL2373291)
Affinity DataIC50:  0.25nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122656(CHEMBL280365 | N-{4-[5-[(Benzyl-methyl-amino)-meth...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50115988(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.300nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122657(CHEMBL21126 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataIC50:  0.300nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in monkey (ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368774(CHEMBL1790963)
Affinity DataIC50:  0.330nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122671(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50115989(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122674(CHEMBL280213 | N-{4-[5-[(Benzyl-methyl-amino)-meth...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368777(CHEMBL2373292)
Affinity DataIC50:  0.420nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368776(CHEMBL1790962)
Affinity DataIC50:  0.420nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Bos taurus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50043324(CHEMBL411171 | c(Cys-Ser-c(Cys-Ser-Ser-Leu-Met-Asp...)
Affinity DataIC50:  0.450nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.5nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor in the membrane ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50115998(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid (AA) release from CHO cells expressing human Leutinizing releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122661(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataIC50:  0.600nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to LHRH receptor in monkey (chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368777(CHEMBL2373292)
Affinity DataIC50:  0.700nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50368772(CHEMBL2373291)
Affinity DataIC50:  0.700nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50115995(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50043322(CHEMBL427748 | c(Cys-Ser-c(Cys-Ser-Ser-Leu-Met-Asp...)
Affinity DataIC50:  0.75nMAssay Description:Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.800nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor the membrane fra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)
Affinity DataIC50:  1nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50122653(6-(4-Amino-phenyl)-5-[(benzyl-methyl-amino)-methyl...)
Affinity DataIC50:  1nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088321(CHEMBL292548 | Dimethyl-(tetrahydro-pyran-4-yl)-{4...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088302(CHEMBL56565 | Dimethyl-(tetrahydro-pyran-4-yl)-(4-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50517802(CHEMBL4457992)
Affinity DataIC50:  1.60nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088322((4-{[7-(4-Ethoxy-phenyl)-2,3-dihydro-benzo[b]oxepi...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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