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Found 146 with Last Name = 'gerlach' and Initial = 'lo'
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270276(CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...)
Affinity DataKi:  10nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270276(CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...)
Affinity DataKi:  110nMAssay Description:Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataKi:  220nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataKi:  890nMAssay Description:Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270277(Benzyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmeth...)
Affinity DataKi:  1.70E+3nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50035719(1-(4-Methyl-benzyl)-1,4,8,11tetraaza-cyclotetradec...)
Affinity DataKi:  2.00E+4nMAssay Description:Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200260(4-bromo-2-[1-(4-bromophenyl)-1H-pyrazole-4-carbony...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200271(4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200266(4-bromo-2-[1-(4-chlorophenyl)-1H-pyrazole-4-carbon...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200265(4-bromo-2-[1-(2-bromophenyl)-1H-pyrazole-4-carbony...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200271(4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200262(4-bromo-2-[1-(3-bromophenyl)-1H-pyrazole-4-carbony...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200247(4-bromo-2-[1-(4-methoxyphenyl)-1H-pyrazole-4-carbo...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200265(4-bromo-2-[1-(2-bromophenyl)-1H-pyrazole-4-carbony...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200260(4-bromo-2-[1-(4-bromophenyl)-1H-pyrazole-4-carbony...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200267(CHEMBL214668 | [3',5'-difluoro-3-(1-phenyl-1H-pyra...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200270(4-chloro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200266(4-bromo-2-[1-(4-chlorophenyl)-1H-pyrazole-4-carbon...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200271(4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...)
Affinity DataIC50:  24nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200262(4-bromo-2-[1-(3-bromophenyl)-1H-pyrazole-4-carbony...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200259(CHEMBL217624 | [4'-chloro-3-(1-phenyl-1H-pyrazole-...)
Affinity DataIC50:  37nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200255(3-(1-phenyl-1H-pyrazole-4-carbonyl)biphenyl-4-ylox...)
Affinity DataIC50:  42nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200277(4-nitro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...)
Affinity DataIC50:  47nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200273(4-methyl-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...)
Affinity DataIC50:  48nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200247(4-bromo-2-[1-(4-methoxyphenyl)-1H-pyrazole-4-carbo...)
Affinity DataIC50:  53nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200254(2-(2-benzoyl-4-bromophenoxy)acetic acid | CHEMBL21...)
Affinity DataIC50:  53nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200276(CHEMBL217167 | {4-bromo-2-[(quinolin-8-ylhydrazono...)
Affinity DataIC50:  54nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200269(2-(4-bromo-2-tert-butylphenoxy)acetic acid | CHEMB...)
Affinity DataIC50:  61nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200264((4-bromo-2-{[(5-phenyl-1,2,4-triazin-3-yl)hydrazon...)
Affinity DataIC50:  89nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200256(4-fluoro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...)
Affinity DataIC50:  108nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200251(2-(4-bromo-2-formylphenoxy)acetic acid | CHEMBL385...)
Affinity DataIC50:  124nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200267(CHEMBL214668 | [3',5'-difluoro-3-(1-phenyl-1H-pyra...)
Affinity DataIC50:  147nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200268(4-methoxy-2-(1-phenyl-1H-pyrazole-4-carbonyl)pheno...)
Affinity DataIC50:  151nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200275(CHEMBL216366 | ethyl 4-bromo-2-(1-phenyl-1H-pyrazo...)
Affinity DataIC50:  165nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200270(4-chloro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...)
Affinity DataIC50:  185nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200277(4-nitro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...)
Affinity DataIC50:  236nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200272(CHEMBL386358 | {4-bromo-2-[(pyridin-2-ylhydrazono)...)
Affinity DataIC50:  255nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200249(2-(4-bromo-2-(isoxazole-5-carbonyl)phenoxy)acetic ...)
Affinity DataIC50:  391nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200269(2-(4-bromo-2-tert-butylphenoxy)acetic acid | CHEMB...)
Affinity DataIC50:  423nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200254(2-(2-benzoyl-4-bromophenoxy)acetic acid | CHEMBL21...)
Affinity DataIC50:  437nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200259(CHEMBL217624 | [4'-chloro-3-(1-phenyl-1H-pyrazole-...)
Affinity DataIC50:  448nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200251(2-(4-bromo-2-formylphenoxy)acetic acid | CHEMBL385...)
Affinity DataIC50:  481nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200255(3-(1-phenyl-1H-pyrazole-4-carbonyl)biphenyl-4-ylox...)
Affinity DataIC50:  485nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200252(2-(2-acetyl-4-bromophenoxy)acetic acid | CHEMBL384...)
Affinity DataIC50:  510nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200258(2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxyacetic a...)
Affinity DataIC50:  510nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200263(CHEMBL217709 | [2-({[(2,4-dichlorophenoxy)acetyl]h...)
Affinity DataIC50:  555nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200273(4-methyl-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...)
Affinity DataIC50:  587nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200276(CHEMBL217167 | {4-bromo-2-[(quinolin-8-ylhydrazono...)
Affinity DataIC50:  643nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200250(2-(4-bromo-2-(hydroxymethyl)phenoxy)acetic acid | ...)
Affinity DataIC50:  886nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200256(4-fluoro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...)
Affinity DataIC50:  1.32E+3nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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