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Found 404 with Last Name = 'ghiron' and Initial = 'c'
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195589(2-amino-1,5-dihydro-7-[[(2S,4R)-2-(hydroxymethyl)-...)
Affinity DataKi:  1nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195593(2-amino-1,5-dihydro-7-[[(2S)-2-(hydroxymethyl)-1-p...)
Affinity DataKi:  2nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195597(2-amino-1,5-dihydro-7-[[N,N-bis-[2-(hydroxy)ethyl]...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195591(2-amino-1,5-dihydro-7-[[[2-(hydroxy)ethyl]amino]me...)
Affinity DataKi:  10.2nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195595(2-amino-1,5-dihydro-7-[[[N-[2-(hydroxy)ethyl]-N-me...)
Affinity DataKi:  30.6nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195588(2-amino-1,5-dihydro-7-[[N-[ethyl]-N-[2-(hydroxy)et...)
Affinity DataKi:  112nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50300802(5-Morpholin-4-ylpentanoic acid(4-pyridin-3-ylpheny...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]epibatidine from rat rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195594(2-amino-1,5-dihydro-7-[[(2S)-2-(methoxymethyl)-1-p...)
Affinity DataKi:  306nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195590(2-amino-1,5-dihydro-7-[[(2S)-2-(aminomethyl)-1-pyr...)
Affinity DataKi:  306nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195596(2-amino-1,5-dihydro-7-[[(2R)-2-(hydroxymethyl)-1-p...)
Affinity DataKi:  316nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]-epibatidine from rat alpha7 nAchR expressed in rat GH4C1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataKi:  660nMAssay Description:Displacement of [3H]epibatidine from rat alpha7 nAChR expressed in GH4C1 cells after 1 hr by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195592(2-amino-1,5-dihydro-7-[[3-(hydroxymethyl)-1-piperi...)
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50319673(1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17744(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...)
Affinity DataIC50:  0.600nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17740(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(4-me...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17735(2,6-dimethylphenyl N-(2-{[3,5-dimethoxy-4-(4-methy...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM50374627(CHEMBL270692)
Affinity DataIC50:  1nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17726(2,6-dimethylphenyl N-(2-methoxyphenyl)-N-(2-{[4-(4...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17728(2,6-dimethylphenyl N-[4-fluoro-2-(propan-2-yloxy)p...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17730(2,6-dimethylphenyl N-[(2,5-dimethoxyphenyl)methyl]...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17734(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17735(2,6-dimethylphenyl N-(2-{[3,5-dimethoxy-4-(4-methy...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17736(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17738(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17739(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17740(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(4-me...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17741(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(morp...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17742(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17743(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17745(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17730(2,6-dimethylphenyl N-[(2,5-dimethoxyphenyl)methyl]...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17744(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17736(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17741(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(morp...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17743(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195589(2-amino-1,5-dihydro-7-[[(2S,4R)-2-(hydroxymethyl)-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17729(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17746(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17734(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17727(2,6-dimethylphenyl N-(4-methoxyphenyl)-N-(2-{[4-(4...)
Affinity DataIC50:  3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50374627(CHEMBL270692)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17738(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17726(2,6-dimethylphenyl N-(2-methoxyphenyl)-N-(2-{[4-(4...)
Affinity DataIC50:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50195593(2-amino-1,5-dihydro-7-[[(2S)-2-(hydroxymethyl)-1-p...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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