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Found 18 with Last Name = 'glickman' and Initial = 'jf'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36511(5-((2-Carboxy-1H-benzo[g]indol-1-yl)methyl)isoxazo...)
Affinity DataIC50:  80nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36510(1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic a...)
Affinity DataIC50:  200nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36508(3-(Carboxymethyl)-4,7-dichloro-1H-indole-2-carboxy...)
Affinity DataIC50:  2.00E+3nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36509(3-(Carboxymethyl)-5,7-dichloro-1H-indole-2-carboxy...)
Affinity DataIC50:  6.00E+3nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36506(2-(Naphtho[2,1-b]thiophen-1-yl)acetic acid, 7 | CI...)
Affinity DataIC50:  7.00E+3nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36505(2-(3-Chlorobenzo[b]thiophen-2-yl)acetic acid, 6 | ...)
Affinity DataIC50:  1.20E+4nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50300194(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50300195(4-Fluoro-2-[3-(1-naphthalen-2-ylmethyl-1H-pyrazol-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50300193(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50300195(4-Fluoro-2-[3-(1-naphthalen-2-ylmethyl-1H-pyrazol-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50300194(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Novartis Institute For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50300193(2-[3-(1-Benzyl-1H-pyrazol-3-yl)-benzenesulfonylami...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36507((R)-1-(benzyloxycarbonyl)indoline-2-carboxylic aci...)
Affinity DataIC50:  5.00E+4nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36504(2-(4-Chlorobenzo[b]thiophen-2-yl)propanoic acid, 5...)
Affinity DataIC50:  8.00E+4nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36500(2-(5-Chlorobenzo[b]thiophen-3-yl)acetic acid, 1 | ...)
Affinity DataIC50: >5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36501(2-(5-chloro-3-methylbenzo[b]thiophen-2-yl)acetic a...)
Affinity DataIC50: >5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36502(2-(6-Methoxybenzofuran-3-yl)acetic acid, 3 | CID73...)
Affinity DataIC50: >5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36503((S)-1-((Benzyloxy)carbonyl)indoline-2-carboxylic a...)
Affinity DataIC50: >5.00E+5nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair