Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Binding affinity to human recombinant LXRbeta ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]T0901317 from human LXRalpha ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Displacement of [3H]T0901317 from human LXRbeta ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair