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Found 747 with Last Name = 'golz' and Initial = 's'
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160276(US9040691, 4)
Affinity DataIC50:  1nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160301(US9040691, 29)
Affinity DataIC50:  1nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160312(US9040691, 40 | US9040691, 41 | US9040691, 42)
Affinity DataIC50:  1.20nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160277(US9040691, 5)
Affinity DataIC50:  1.30nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160315(US9040691, 43)
Affinity DataIC50:  1.90nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160283(US9040691, 11)
Affinity DataIC50:  1.90nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160273(US9040691, 1)
Affinity DataIC50:  2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160279(US9040691, 7)
Affinity DataIC50:  2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160289(US9040691, 17)
Affinity DataIC50:  2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160302(US9040691, 30)
Affinity DataIC50:  2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160288(US9040691, 16)
Affinity DataIC50:  2.60nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160274(US9040691, 2)
Affinity DataIC50:  2.80nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160283(US9040691, 11)
Affinity DataIC50:  3nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160309(US9040691, 37)
Affinity DataIC50: <3nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160312(US9040691, 40 | US9040691, 41 | US9040691, 42)
Affinity DataIC50:  3.20nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160312(US9040691, 40 | US9040691, 41 | US9040691, 42)
Affinity DataIC50:  3.5nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160316(US9040691, 44)
Affinity DataIC50:  3.80nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160275(US9040691, 3)
Affinity DataIC50:  4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160285(US9040691, 13)
Affinity DataIC50:  4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160303(US9040691, 31)
Affinity DataIC50:  4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160304(US9040691, 32)
Affinity DataIC50:  4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160310(US9040691, 38)
Affinity DataIC50:  4nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160306(US9040691, 34)
Affinity DataIC50:  4.10nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160280(US9040691, 35 | US9040691, 36 | US9040691, 8)
Affinity DataIC50:  4.40nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300498(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...)
Affinity DataIC50:  5.17nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300495(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(4-m...)
Affinity DataIC50:  5.20nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160286(US9040691, 14)
Affinity DataIC50:  5.30nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160311(US9040691, 39)
Affinity DataIC50:  5.70nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160281(US9040691, 9)
Affinity DataIC50:  5.70nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160284(US9040691, 12)
Affinity DataIC50:  5.90nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160279(US9040691, 7)
Affinity DataIC50:  6.70nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160280(US9040691, 35 | US9040691, 36 | US9040691, 8)
Affinity DataIC50:  6.90nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300498(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...)
Affinity DataIC50:  7.72nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300675(N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- {[2-(mo...)
Affinity DataIC50:  7.85nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160282(US9040691, 10)
Affinity DataIC50:  8nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300545(N-{6-[4-(dimethylamino)phenyl]pyridin-3-yl}-3-{[(2...)
Affinity DataIC50:  8.80nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300439(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(mor...)
Affinity DataIC50:  9nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300440(3-{[2-(morpholin-4-yl)propanoyl]amino}-N-(6-phenyl...)
Affinity DataIC50:  10.4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300677(N-[6-(3-fluorophenyl)pyridin-3- yl]-3-{[2-(8-oxa-3...)
Affinity DataIC50:  11nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300496(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(4-m...)
Affinity DataIC50:  11nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300440(3-{[2-(morpholin-4-yl)propanoyl]amino}-N-(6-phenyl...)
Affinity DataIC50:  11.2nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300548(N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[(2R)-2-(morp...)
Affinity DataIC50:  12.6nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300436(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-[(8-oxa-3-aza...)
Affinity DataIC50:  13nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300497(3-({[1-(4-cyclopropylpiperazin-1-yl)cyclopropyl]ca...)
Affinity DataIC50:  13nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300547(N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[(2R)-2-(morp...)
Affinity DataIC50:  14nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300439(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(mor...)
Affinity DataIC50:  14.2nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300499(N-[6-(3-fluorophenyl)pyridin-3-yl]-3-{[2-(morpholi...)
Affinity DataIC50:  14.8nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM160305(US9040691, 33)
Affinity DataIC50:  15nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300511(4-methoxy-3-({[1-(morpholin-4-yl)cyclopropyl]carbo...)
Affinity DataIC50:  15nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300564(4-(cyclopropyloxy)-N-[6-(2-fluorophenyl)pyridin-3-...)
Affinity DataIC50:  16.6nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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