Affinity DataKi: 0.00800nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.0140nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.0230nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.0350nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 20.5nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:In vitro inhibitory activity against Human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Ratio of Koff to that of Kon was determined on human leukocyte elastase(HLE)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase in human cellMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibitory activity against Human leukocyte elastase was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Activity of the compound to bind against [3H]-LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:In vitro inhibitory activity against rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Activity of the compound to bind against [3H]-LTD4 radioligand in guinea pigMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of rat 5-LipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase using guinea pig supernatantMore data for this Ligand-Target Pair