Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Compound was evaluated in vitro for the inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer proteinMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of c-Jun N-Terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer protein, reported from fungusMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 147nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of c-Jun N-Terminal kinase 1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against c-Jun N-Terminal kinase 2More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 255nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Serono Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 273nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair