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Found 146 with Last Name = 'gotteland' and Initial = 'jp'
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032850(CHEMBL27885 | [3-([3,3']Bithiophenyl-5-ylmethoxy)-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  30nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032853(2-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169985(4-(2-(4-(benzo[d]thiazol-2(3H)-ylidene(cyano)methy...)
Affinity DataIC50:  41nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated in vitro for the inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032856(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  60nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169980(CHEMBL363254 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  65nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032837(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-Jun N-Terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032847(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032830(CHEMBL107568 | {3-[(Dimethyl-o-tolyl-silanyl)-meth...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  80nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer protein, reported from fungusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169998(CHEMBL191581 | CHEMBL254651 | [3H-Benzothiazol-(2Z...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170008(CHEMBL372708 | {2-[2-(4-Amino-phenyl)-ethylamino]-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070337(CHEMBL27154 | [3,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032848((6,6-Dimethyl-hepta-2,4-diynyl)-{3-[(dimethyl-o-to...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070344(CHEMBL26950 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50288841((3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-ami...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50291660(CHEMBL16178 | [3-([3,3']Bithiophenyl-5-ylmethoxy)-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032834(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032832(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032842(CHEMBL108144 | {3-[(Benzyl-dimethyl-silanyl)-metho...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169999(CHEMBL371113 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  143nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170017(CHEMBL189841 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  147nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032844(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of c-Jun N-Terminal kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50158551(CHEMBL383955 | N-((5-(4-(1H-benzo[d][1,2,3]triazol...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032840(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(2-...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070341(CHEMBL26151 | Pyridine-3-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070345(CHEMBL26964 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070343(CHEMBL26596 | Thiazole-2-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070350(CHEMBL284197 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070331(4-Cyano-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070346(CHEMBL27941 | [2,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50032835((3-{[(4-Bromo-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169959(2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against c-Jun N-Terminal kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070342(CHEMBL26077 | Thiophene-2-sulfonic acid cyclopropy...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169966((2Z)-1,3-benzothiazol-2(3H)-ylidene(2-chloropyrimi...)
Affinity DataIC50:  250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50170001(CHEMBL364637 | [3H-Benzothiazol-(2Z)-ylidene]-[2-(...)
Affinity DataIC50:  250nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070349(CHEMBL26597 | Thiophene-3-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070333(CHEMBL281666 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  255nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50291661(CHEMBL267332 | [3-(3-Azido-phenyl)-prop-2-ynyl]-[3...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50169965(CHEMBL363253 | [3H-Benzothiazol-(2Z)-ylidene]-{2-[...)
Affinity DataIC50:  273nMAssay Description:Inhibition of rat c-Jun N-terminal kinase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070348(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-{3-[3-(t...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50070339(4-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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