Compile Data Set for Download or QSAR
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Found 46 with Last Name = 'groaning' and Initial = 'md'
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139717(CHEMBL166429 | Phenyl-thioacetic acid [1-pyridin-3...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139728(CHEMBL168334 | Phenyl-thioacetic acid [1-(2-hydrox...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139719(3-(3-Bromo-benzyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139733(3-(2-Bromo-benzyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139737(CHEMBL168424 | Phenyl-thioacetic acid [1-(2-hydrox...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139723(3-(2,3-Difluoro-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139713(3-(3,4-Dimethyl-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139719(3-(3-Bromo-benzyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]...)
Affinity DataKi:  40nMAssay Description:Binding affinity for rat adenosine A2A receptor by displacement of [3H]-SCH-58,261More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139727(3-(3,4-Dichloro-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  40nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139727(3-(3,4-Dichloro-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  40nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139723(3-(2,3-Difluoro-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  40nMAssay Description:Binding affinity for rat adenosine A2A receptor by displacement of [3H]-SCH-58,261More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139735(2-[5-(3,4-Dichloro-benzyl)-2H-[1,2,4]triazol-3-yl]...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139738(3-(3,4-Difluoro-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139740(5-(3-Methoxy-phenyl)-3-(3-nitro-benzyl)-1H-[1,2,4]...)
Affinity DataKi:  80nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139731(3-(3,4-Dichloro-benzyl)-5-(2,3-dimethoxy-phenyl)-1...)
Affinity DataKi:  90nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139713(3-(3,4-Dimethyl-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  90nMAssay Description:Binding affinity for rat adenosine A2A receptor by displacement of [3H]-SCH-58,261More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139725(5-Benzo[1,3]dioxol-5-yl-3-(3,4-dichloro-benzyl)-1H...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139722(CHEMBL166424 | Phenyl-thioacetic acid [1-(2-hydrox...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139718(5-(3-Methoxy-phenyl)-3-naphthalen-2-ylmethyl-1H-[1...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139719(3-(3-Bromo-benzyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]...)
Affinity DataKi:  100nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139736(CHEMBL168481 | Phenyl-thioacetic acid [1-pyridin-2...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139718(5-(3-Methoxy-phenyl)-3-naphthalen-2-ylmethyl-1H-[1...)
Affinity DataKi:  400nMAssay Description:Binding affinity for rat adenosine A2A receptor by displacement of [3H]-SCH-58,261More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139712(3-(4-Azido-phenyl)-5-[3-(2,5-dihydro-pyrrol-1-ylme...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139711(5-(3,4-Dichloro-phenyl)-3-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139716(3-Cyclohexylmethyl-5-(3-methoxy-phenyl)-1H-[1,2,4]...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139732(2-(5-Phenyl-1H-[1,2,4]triazol-3-yl)-phenol | CHEMB...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139723(3-(2,3-Difluoro-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  900nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139714(5-[2-(3,4-Dichloro-phenyl)-ethyl]-3-(3-methoxy-phe...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139724(5-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-3-(3-pyrroli...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139739(CHEMBL167703 | Phenyl-thioacetic acid [1-quinolin-...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139726(CHEMBL166104 | Phenyl-thioacetic acid [1-(2-hydrox...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139713(3-(3,4-Dimethyl-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139714(5-[2-(3,4-Dichloro-phenyl)-ethyl]-3-(3-methoxy-phe...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139727(3-(3,4-Dichloro-benzyl)-5-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139734(CHEMBL424526 | Phenyl-thioacetic acid [1-quinolin-...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139718(5-(3-Methoxy-phenyl)-3-naphthalen-2-ylmethyl-1H-[1...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139721(CHEMBL166548 | Phenyl-thioacetic acid [1-(2-hydrox...)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139720(CHEMBL167010 | Phenyl-thioacetic acid [1-(2-hydrox...)
Affinity DataKi:  4.70E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139729(CHEMBL354547 | Phenyl-thioacetic acid [1-phenyl-me...)
Affinity DataKi: >5.20E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139730(1-[5-(3-Methoxy-phenyl)-1H-[1,2,4]triazol-3-ylmeth...)
Affinity DataKi: >5.20E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139741(3-[5-(3,4-Dichloro-benzyl)-2H-[1,2,4]triazol-3-yl]...)
Affinity DataKi: >5.20E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139742(1-[3-(2-Hydroxy-5-methyl-phenyl)-4,5-dihydro-pyraz...)
Affinity DataKi: >5.20E+3nMAssay Description:Binding affinity for human adenosine A2A receptor by displacement of [3H]-SCH-58,261; inactiveMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139715(CHEMBL352821 | Phenyl-thioacetic acid [1-(2-hydrox...)
Affinity DataKi: >5.20E+3nMAssay Description:Binding affinity towards human recombinant adenosine A2A receptor by displacement of [3H]-SCH-58,261 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139711(5-(3,4-Dichloro-phenyl)-3-(3-methoxy-phenyl)-1H-[1...)
Affinity DataKi:  6.10E+3nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139712(3-(4-Azido-phenyl)-5-[3-(2,5-dihydro-pyrrol-1-ylme...)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50139724(5-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-3-(3-pyrroli...)
Affinity DataKi:  7.60E+3nMAssay Description:Binding affinity for human adenosine A1 receptor by displacement of [3H]-DPCPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed