BindingDB PrimarySearch_ki

Found 73 with Last Name = 'grubbs' and Initial = 'cj'

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445061(CHEMBL3098772)

Kd: 1.55E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)

Kd: 1.56E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50017994(CHEMBL3289658)

Kd: 1.75E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018001(CHEMBL3289659)

Kd: 1.86E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445062(CHEMBL3098771)

Kd: 1.88E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)

Kd: 1.89E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018004(CHEMBL3289657)

Kd: 2.24E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018005(CHEMBL3289660)

Kd: 2.33E+3nMAssay Description:Agonist activity at human RXR-alpha-ligand binding domain homodimers assessed as coactivator recruitment by measuring GRIP1 binding to receptor by is...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018001(CHEMBL3289659)

Kd: 8nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018005(CHEMBL3289660)

Kd: 10nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)

Kd: 14nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50017994(CHEMBL3289658)

Kd: 15nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018004(CHEMBL3289657)

Kd: 18nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(RAT)
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445060(CHEMBL3098773)

EC50: 19nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445060(CHEMBL3098773)

Kd: 25nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)

Kd: 26nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445062(CHEMBL3098771)

Kd: 33nMAssay Description:Binding affinity to human RXR-alpha-ligand binding domain homodimers by fluorescence quenching methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)

EC50: 40nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50017994(CHEMBL3289658)

EC50: 100nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(RAT)
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)

EC50: 110nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(RAT)
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50017994(CHEMBL3289658)

EC50: 110nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)

EC50: 120nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445060(CHEMBL3098773)

EC50: 120nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018001(CHEMBL3289659)

EC50: 160nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(RAT)
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445062(CHEMBL3098771)

EC50: 400nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(RAT)
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018004(CHEMBL3289657)

EC50: 440nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018005(CHEMBL3289660)

EC50: 620nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018004(CHEMBL3289657)

EC50: 720nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445062(CHEMBL3098771)

EC50: 820nMAssay Description:Agonist activity at Gal4-fused human RXR-alpha expressed in HEK293 cells assessed as receptor-mediated transcriptional activity treated 24 hrs after ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(RAT)
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018005(CHEMBL3289660)

EC50: 880nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(RAT)
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50018001(CHEMBL3289659)

EC50: >1.00E+3nMAssay Description:Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)

Kd: 1.81E+3nMAssay Description:Binding affinity to human RXRalpha LBD after 15 mins by isothermal titration calorimetry assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)

Kd: 1.59E+3nMAssay Description:Binding affinity to human RXRalpha LBD after 15 mins by isothermal titration calorimetry assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50445062(CHEMBL3098771)

Kd: 1.33E+3nMAssay Description:Binding affinity to human RXRalpha LBD after 15 mins by isothermal titration calorimetry assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123609(CHEMBL3622724)

Kd: 1.21E+3nMAssay Description:Binding affinity to human RXRalpha LBD after 15 mins by isothermal titration calorimetry assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123610(CHEMBL3622725)

Kd: 470nMAssay Description:Binding affinity to human RXRalpha LBD after 15 mins by isothermal titration calorimetry assayMore data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123611(CHEMBL3622721)

EC50: 215nMAssay Description:Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer...More data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123612(CHEMBL3622722)

EC50: 23nMAssay Description:Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer...More data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123614(CHEMBL3622723)

EC50: 19nMAssay Description:Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123609(CHEMBL3622724)

EC50: 22nMAssay Description:Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer...More data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123610(CHEMBL3622725)

EC50: 80nMAssay Description:Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer...More data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)

EC50: 118nMAssay Description:Agonist activity at RXRalpha LBD (unknown origin) expressed in CV1 cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123615(CHEMBL3622720)

EC50: 50nMAssay Description:Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer...More data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123616(CHEMBL3622719)

EC50: 30nMAssay Description:Agonist activity at human RXRalpha LBD expressed in HEK293 cells transfected with Gal4 reporter assessed as increase of transcription by dual lucifer...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123610(CHEMBL3622725)

Kd: 150nMAssay Description:Binding affinity to human RXRalpha LBD by fluorescence quenching methodMore data for this Ligand-Target Pair

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Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123609(CHEMBL3622724)

Kd: 9nMAssay Description:Binding affinity to human RXRalpha LBD by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123614(CHEMBL3622723)

Kd: 35nMAssay Description:Binding affinity to human RXRalpha LBD by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123612(CHEMBL3622722)

Kd: 14nMAssay Description:Binding affinity to human RXRalpha LBD by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123611(CHEMBL3622721)

Kd: 125nMAssay Description:Binding affinity to human RXRalpha LBD by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Retinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL

PNG

BDBM50123615(CHEMBL3622720)

Kd: 34nMAssay Description:Binding affinity to human RXRalpha LBD by fluorescence quenching methodMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

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