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Found 1483 with Last Name = 'haap' and Initial = 'w'
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263570(CHEMBL4066422)
Affinity DataKi:  1nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263570(CHEMBL4066422)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263572(CHEMBL4092050)
Affinity DataKi:  2nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263634(CHEMBL4073014)
Affinity DataKi:  2nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263577(CHEMBL4099651)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM210850(US9290467, 20)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM210854(US9290467, 24 | US9290467, 25 | US9290467, 26)
Affinity DataKi:  2.5nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263578(CHEMBL4064172)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263632(CHEMBL4080286)
Affinity DataKi:  2.90nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263647(CHEMBL4099905)
Affinity DataKi:  3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM210859(US9290467, 29)
Affinity DataKi:  3nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263571(CHEMBL4062591)
Affinity DataKi:  3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50295588(5-chloro-N-((3S,4S)-1-(2-(2-fluoro-4-(2-oxopyridin...)
Affinity DataKi:  3nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Oryctolagus cuniculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324743((3R,4R)-1-(2,2-DIFLUORO-ETHYL)-PYRROLIDINE-3,4-DIC...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to rabbit factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263569(CHEMBL4087751)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263689(CHEMBL4064430)
Affinity DataKi:  4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263622(CHEMBL4065829)
Affinity DataKi:  4nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263574(CHEMBL4065847)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263573(CHEMBL4080708)
Affinity DataKi:  4.80nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263573(CHEMBL4080708)
Affinity DataKi:  4.80nMAssay Description:Agonist activity at human SP/Myc epitope-tagged muscarinic M1 receptor expressed in HEK293T cells assessed as RLuc8-fused Galphaq activation after 2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263576(CHEMBL4072767)
Affinity DataKi:  5.20nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263584(CHEMBL4084294)
Affinity DataKi:  5.40nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263568(CHEMBL4098931)
Affinity DataKi:  5.60nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263583(CHEMBL4091192)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50295581(4-chloro-N-(1-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-y...)
Affinity DataKi:  6nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50295583(4-chloro-N-(1-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-y...)
Affinity DataKi:  6nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263569(CHEMBL4087751)
Affinity DataKi:  6.10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263684(CHEMBL4093712)
Affinity DataKi:  7nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263683(CHEMBL4101430)
Affinity DataKi:  7nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263571(CHEMBL4062591)
Affinity DataKi:  7.30nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263638(CHEMBL4102966)
Affinity DataKi:  7.40nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263584(CHEMBL4084294)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263685(CHEMBL4082483)
Affinity DataKi:  7.40nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263686(CHEMBL4086533)
Affinity DataKi:  7.40nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263633(CHEMBL4104507)
Affinity DataKi:  7.40nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263637(CHEMBL4078688)
Affinity DataKi:  7.40nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263636(CHEMBL4065096)
Affinity DataKi:  7.40nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324757((3R,4R)-N3-(4-chlorophenyl)-1-(N,N-dimethylsulfamo...)
Affinity DataKi:  8nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263635(CHEMBL4065483)
Affinity DataKi:  8nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50295585((R)-4-chloro-N-(1-(2-(2-fluoro-4-(2-oxopyridin-1(2...)
Affinity DataKi:  8nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324771((3R,4R)-N3-(5-chloropyridin-2-yl)-N4-(2-fluoro-4-(...)
Affinity DataKi:  8nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263568(CHEMBL4098931)
Affinity DataKi:  8.70nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263640(CHEMBL4084048)
Affinity DataKi:  9nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324755((3R,4R)-N-(4-CHLOROPHENYL)-N'-[2-FLUORO-4-(2-OXOPY...)
Affinity DataKi:  9nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263641(CHEMBL4094298)
Affinity DataKi:  9nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263593(CHEMBL4096787)
Affinity DataKi:  10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324758((3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(2-oxop...)
Affinity DataKi:  10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM210853(US9290467, 23)
Affinity DataKi:  10nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50295589(5-chloro-N-((3S,4S)-4-ethoxy-1-(2-(2-fluoro-4-(2-o...)
Affinity DataKi:  10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324754((3R,4R)-1-SULFAMOYL-PYRROLIDINE-3,4-DICARBOXYLIC A...)
Affinity DataKi:  10nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
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