TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibitory activity against mammalian Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inhibitory concentration against dihydrofolate reductase (DHFR) enzyme isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells. value mentioned is from li...More data for this Ligand-Target Pair
Affinity DataIC50: 1.18nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against Dihydrofolate reductase (DHFR) isolated from CCRF-CEM human leukemia cells in experiment 2More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against dihydrofolate reductase enzyme (DHFR) enzyme isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Compound was evaluated as inhibitor of human Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Compound was evaluated as inhibitor of human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Compound was evaluated as inhibitor of human Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated as inhibitor of human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated as inhibitor of human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Compound was evaluated as inhibitor of human Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was evaluated as inhibitor of human Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Compound was evaluated as inhibitor of human Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Compound was evaluated as inhibitor of human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was evaluated as inhibitor of human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Compound was evaluated as inhibitor of human Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory concentration against human Folyl-polyglutamate synthase isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Compound was evaluated as inhibitor of human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+5nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+5nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+5nMAssay Description:Compound was evaluated as inhibitor of Escherichia coli Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibitory concentration against human Folyl-polyglutamate synthase isolated from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair