TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 174nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 281nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 306nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 397nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 416nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 455nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 461nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 589nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 709nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 825nMAssay Description:Activity at human mGluR5 assessed as effect on glutamate-induced calcium ion mobilization by FLIPRMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 862nMAssay Description:Activity at human mGluR5d assessed as inhibition of glutamate-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D MöLndal
Curated by ChEMBL
Astrazeneca R&D MöLndal
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair