Found 509 with Last Name = 'han' and Initial = 'sj' TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to GST-tagged EED (unknown origin) assessed as inhibition constant incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity to GST-tagged EED (unknown origin) assessed as inhibition constant incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 700nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 990nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.22E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.41E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.59E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.68E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.95E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.41E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.52E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.94E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.25E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.57E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.82E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.69E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.14E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.38E+4nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 0.890nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate in presence of ATP measured after 45 mins by HTRF assay relative to controlMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate in presence of ATP measured after 45 mins by HTRF assay relative to controlMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ENPP1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of His-tagged EED (unknown origin) incubated for 30 mins in presence of biotinylated H3K27me3 peptide (19 to 33 aa) by alpha screening com...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of EED (unknown origin)More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human DGAT1 expressed in human Hep3B cells incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid sc...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Sanquan College Of Xinxiang Medical University
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse DGAT1 incubated for 60 mins using didecanoyl glycerol and [14C]decanoyl-CoA substrate by liquid scintillation counting and lumino...More data for this Ligand-Target Pair
