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Found 208 with Last Name = 'harada' and Initial = 'j'
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296527(CHEMBL552269 | N-(5-(3,5-difluorobenzyl)thiazol-2-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296528(CHEMBL557445 | N-(5-(4-fluoro-3-(trifluoromethyl)b...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296295(CHEMBL552173 | N-(5-(3,5-bis(trifluoromethyl)benzy...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296528(CHEMBL557445 | N-(5-(4-fluoro-3-(trifluoromethyl)b...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296295(CHEMBL552173 | N-(5-(3,5-bis(trifluoromethyl)benzy...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296526(CHEMBL552126 | N-(5-(3,5-dichlorobenzyl)thiazol-2-...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296531(CHEMBL550800 | N-(5-(3,4-dichlorobenzyl)thiazol-2-...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296522(CHEMBL561588 | N-(5-(3-chlorobenzyl)thiazol-2-yl)-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296531(CHEMBL550800 | N-(5-(3,4-dichlorobenzyl)thiazol-2-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296529(CHEMBL552270 | N-(5-(3-chloro-4-fluorobenzyl)thiaz...)
Affinity DataIC50:  1nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296526(CHEMBL552126 | N-(5-(3,5-dichlorobenzyl)thiazol-2-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296294(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  2nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296529(CHEMBL552270 | N-(5-(3-chloro-4-fluorobenzyl)thiaz...)
Affinity DataIC50:  2nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296533(3-(4-methoxyphenyl)-N-(5-(3-(trifluoromethyl)benzy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296521(CHEMBL559108 | N-(5-(3-fluorobenzyl)thiazol-2-yl)-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296530(CHEMBL557652 | N-(5-(3,4-difluorobenzyl)thiazol-2-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296527(CHEMBL552269 | N-(5-(3,5-difluorobenzyl)thiazol-2-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296294(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  3nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296524(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  3nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296533(3-(4-methoxyphenyl)-N-(5-(3-(trifluoromethyl)benzy...)
Affinity DataIC50:  3nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296513(4-(2-hydroxyethoxy)-3-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  3nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296524(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  4nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296522(CHEMBL561588 | N-(5-(3-chlorobenzyl)thiazol-2-yl)-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296534(6-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiazol-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296528(CHEMBL557445 | N-(5-(4-fluoro-3-(trifluoromethyl)b...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296525(CHEMBL556495 | N-(5-(2,5-dichlorobenzyl)thiazol-2-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296534(6-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiazol-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296522(CHEMBL561588 | N-(5-(3-chlorobenzyl)thiazol-2-yl)-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296530(CHEMBL557652 | N-(5-(3,4-difluorobenzyl)thiazol-2-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296513(4-(2-hydroxyethoxy)-3-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  10nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296521(CHEMBL559108 | N-(5-(3-fluorobenzyl)thiazol-2-yl)-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296526(CHEMBL552126 | N-(5-(3,5-dichlorobenzyl)thiazol-2-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296531(CHEMBL550800 | N-(5-(3,4-dichlorobenzyl)thiazol-2-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296529(CHEMBL552270 | N-(5-(3-chloro-4-fluorobenzyl)thiaz...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296532(CHEMBL561530 | N-(5-(3-fluoro-4-methylbenzyl)thiaz...)
Affinity DataIC50:  22nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296295(CHEMBL552173 | N-(5-(3,5-bis(trifluoromethyl)benzy...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50433158(CHEMBL2377769)
Affinity DataIC50:  26nMAssay Description:Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296530(CHEMBL557652 | N-(5-(3,4-difluorobenzyl)thiazol-2-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296521(CHEMBL559108 | N-(5-(3-fluorobenzyl)thiazol-2-yl)-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50433138(CHEMBL2377620)
Affinity DataIC50:  41nMAssay Description:Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50433140(CHEMBL2377621)
Affinity DataIC50:  46nMAssay Description:Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296524(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296537(3,4-dimethoxy-N-(5-(3-(trifluoromethyl)benzyl)thia...)
Affinity DataIC50:  76nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50433157(CHEMBL2377766)
Affinity DataIC50:  77nMAssay Description:Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296532(CHEMBL561530 | N-(5-(3-fluoro-4-methylbenzyl)thiaz...)
Affinity DataIC50:  82nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50387683(CHEMBL2058359)
Affinity DataIC50:  91nMAssay Description:Inhibition of mouse FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50387683(CHEMBL2058359)
Affinity DataIC50:  91nMAssay Description:Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50387683(CHEMBL2058359)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50433128(CHEMBL2377611)
Affinity DataIC50:  100nMAssay Description:Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLong-chain fatty acid transport protein 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50433139(CHEMBL2377622)
Affinity DataIC50:  100nMAssay Description:Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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