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Found 55 with Last Name = 'hattori' and Initial = 't'
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459874(CHEMBL4226259)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459869(CHEMBL4227715)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)
Affinity DataIC50:  4.80nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)
Affinity DataIC50:  5.70nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102044(CHEMBL2373002 | Derivative of T140 peptide)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50096735(CHEMBL2372983 | Compound T140)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102037(CHEMBL2372993 | Derivative of T140 peptide)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102036(CHEMBL2372985 | Derivative of T140 peptide)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102040(CHEMBL2372994 | T140)
Affinity DataIC50:  23nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102032(CHEMBL2373001 | Derivative of T140 peptide)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459873(CHEMBL4225186)
Affinity DataIC50:  27nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279265(CHEMBL4162041)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102035(CHEMBL2372997 | Derivative of T140 peptide)
Affinity DataIC50:  51nMAssay Description:Inhibitory concentration determined on an HIV infection model mediated by CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459875(CHEMBL4226844)
Affinity DataIC50:  53nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459868(CHEMBL4225339)
Affinity DataIC50:  54nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279272(CHEMBL4164385)
Affinity DataIC50:  67nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50:  86nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50:  94nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459871(CHEMBL4226314)
Affinity DataIC50:  190nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459866(CHEMBL4226899)
Affinity DataIC50:  190nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279273(CHEMBL4160980)
Affinity DataIC50:  360nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral viral infection of MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: >1.00E+3nMAssay Description:Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459870(CHEMBL4227287)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459867(CHEMBL4226575)
Affinity DataIC50:  1.50E+3nMAssay Description:Binding affinity to androgen receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50328152(CHEMBL1257423 | N-(2-hydroxyethyl)-3-(6-(4-(triflu...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279274(CHEMBL4172268)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50325999(3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
National Institute Of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50459872(CHEMBL4227353)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [17-alpha-methyl-H-3] mibolerone from wild-type androgen receptor (unknown origin) expressed in human Freestyle293F cells measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50096735(CHEMBL2372983 | Compound T140)
Affinity DataEC50:  3.30nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102046(CHEMBL2372989 | Derivative of T140 peptide)
Affinity DataEC50:  2.70nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102031(CHEMBL2372986 | Derivative of T140 peptide)
Affinity DataEC50:  68nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102034(CHEMBL2372995 | Derivative of T140 peptide)
Affinity DataEC50:  6.80nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102044(CHEMBL2373002 | Derivative of T140 peptide)
Affinity DataEC50:  2.80nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102032(CHEMBL2373001 | Derivative of T140 peptide)
Affinity DataEC50:  4.60nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102035(CHEMBL2372997 | Derivative of T140 peptide)
Affinity DataEC50:  0.5nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50145605(4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofura...)
Affinity DataEC50:  88nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102036(CHEMBL2372985 | Derivative of T140 peptide)
Affinity DataEC50:  0.400nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102037(CHEMBL2372993 | Derivative of T140 peptide)
Affinity DataEC50:  0.600nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102040(CHEMBL2372994 | T140)
Affinity DataEC50:  4nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataEC50:  7.90nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102048(CHEMBL2372999 | Derivative of T140 peptide)
Affinity DataEC50:  6.60nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102047(CHEMBL2373004 | Derivative of T140 peptide)
Affinity DataEC50:  1.20nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50102045(CHEMBL2373003 | Derivative of T140 peptide)
Affinity DataEC50:  40nMAssay Description:Effective concentration for 50% protection of HIV-induced cytopathogenicity in MT-4 cells on the MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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