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Found 48 with Last Name = 'heckman' and Initial = 'g'
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226415(CHEMBL3142312)
Affinity DataKi:  0.880nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020671(13-(2-Amino-ethyl)-19-benzyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016752(CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...)
Affinity DataKi:  1.5nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226412(CHEMBL3142332)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226410(CHEMBL3142318)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226411(CHEMBL3142329)
Affinity DataKi:  1.90nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226417(CHEMBL3142331)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020669(13-(2-Amino-ethyl)-19-benzyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226413(CHEMBL2369777)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020665(13-(2-Amino-ethyl)-19-benzyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016752(CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...)
Affinity DataKi:  2.90nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016756(CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...)
Affinity DataKi:  3.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020667(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226416(CHEMBL2369525)
Affinity DataKi:  3.90nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020654(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  3.90nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226414(CHEMBL2369778)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016753(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016753(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016757(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016757(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016747(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016747(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020675(1-[13-Benzyl-7-carbamoylmethyl-16-(4-ethoxy-benzyl...)
Affinity DataKi:  5.30nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020666(13-(2-Amino-ethyl)-19-benzyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  5.80nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  5.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016756(CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...)
Affinity DataKi:  6nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020673(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020653(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  6.40nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016755(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  6.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016755(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  6.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016763(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016763(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226418(CHEMBL3142313)
Affinity DataKi:  7.80nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016754(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  8.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020674(1-[13-Benzyl-7-carbamoylmethyl-16-(4-ethoxy-benzyl...)
Affinity DataKi:  8.90nMAssay Description:Compound was tested for inhibition against V2 vasopressin receptor in pig renal medullary membrane preparations.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016761(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  9.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016762(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  11nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016750(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  11nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020672(13-(2-Amino-ethyl)-19-benzyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  13nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020668(2-{[13-(2-Amino-ethyl)-19-benzyl-22-(4-ethoxy-benz...)
Affinity DataKi:  23nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016749(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  27nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016759(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  28nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016746(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  28nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50020670((2-{[13-(2-Amino-ethyl)-19-benzyl-22-(4-ethoxy-ben...)
Affinity DataKi:  41nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016748(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  42nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016758(2-[20-Benzyl-23-(4-ethoxy-benzyl)-11-(2-hydroxy-py...)
Affinity DataKi:  130nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50016751(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  490nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed