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Found 1579 with Last Name = 'hedley' and Initial = 'sj'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131840(CHEMBL3633142)
Affinity DataIC50:  50nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131839(CHEMBL3633141)
Affinity DataIC50:  348nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131841(CHEMBL3633143)
Affinity DataIC50:  386nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131842(CHEMBL3633151)
Affinity DataIC50:  521nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataIC50:  1.05E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  320nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  290nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  220nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  0.960nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  220nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  130nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  430nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  140nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  30nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  81nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131843(CHEMBL3633152)
Affinity DataKd:  410nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131844(CHEMBL3633349)
Affinity DataKd:  310nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50131844(CHEMBL3633349)
Affinity DataKd:  2.60nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269868((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  12nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269868((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  0.110nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269870((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  30nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269870((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  0.900nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360102((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  13nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  17nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  21nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  0.860nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360103((1S,2R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  0.210nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269877((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  0.690nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269877((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  39nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269879((1S,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  0.880nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269879((1S,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  29nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269881((1S,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  3.30nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269881((1S,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  25nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269883(1S,2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl...)
Affinity DataEC50:  0.460nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269884((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(6-metho...)
Affinity DataEC50:  8.90nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269884((1S,2R)—N-(4-(2,6-dimethoxyphenyl)-5-(6-metho...)
Affinity DataEC50:  0.260nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269886((2S)—N-(4-(2,6-dimethoxyphenyl)-5-(5-ethenyl-...)
Affinity DataEC50:  11nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360117((2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-ethyl-3-pyrid...)
Affinity DataEC50:  7.90nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360118((2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-ethyl-3-pyrid...)
Affinity DataEC50:  6.70nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360119((2S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-ethyl-3-pyrid...)
Affinity DataEC50:  6.30nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360120((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Affinity DataEC50:  1.30nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360121((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Affinity DataEC50:  0.440nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360122((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Affinity DataEC50:  7.10nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360123((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Affinity DataEC50:  3.5nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360124((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Affinity DataEC50:  12.6nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM360125((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-...)
Affinity DataEC50:  0.340nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270010((1S,2R)-1-(5-chloro-2-pyrimidinyl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  2.5nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269897((1R,2S)-1-(5-chloropyrimidin-2-yl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  0.270nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269898((1R,2S)-1-(5-chloropyrimidin-2-yl)-N-(4-(2,6-dimet...)
Affinity DataEC50:  0.530nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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