TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of thymidin synthaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Inhibition of human Thymidylate synthase by uncompetitive bindingMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of human Thymidylate synthase by noncompetitive bindingMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of ERalpha expressed in human tumor cellsMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of thymidin synthaseMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human microsomal CYP2D6 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human microsomal CYP2C9 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human microsomal CYP2C19 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human microsomal CYP3A4 expressed in baculovirus infected BTI-TN-5B1-4 cells incubated for 30 mins by luciferase assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Institute Of Theoretical Studies Ggmbh
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DHFR using folic aid as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataIC50: 9.93E+4nMAssay Description:Inhibition of human ERG in membranes incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair