Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.0 T: 2°CAssay Description:The in vitro kinase activities of wild type or mutants were determined by measuring phosphorylation of biotinylated-MEK protein using Perkin-Elmer s ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University of Pennsylvania
University of Pennsylvania
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:The in vitro kinase activities of wild type or mutants were determined by measuring phosphorylation of biotinylated-MEK protein using Perkin-Elmer s ...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University of Pennsylvania
University of Pennsylvania
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University of Pennsylvania
University of Pennsylvania
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University of Pennsylvania
University of Pennsylvania
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University of Pennsylvania
University of Pennsylvania
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) according to the manufacturer instructions.More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization-based kinase in vitro assay using human PI3K alpha purchased from Echelon Biosciences and p110 alpha/p85 alpha from Upstate...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair