Affinity DataKi: 0.0340nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0690nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Inhibition of human ERG expressed in HEK cells assessed as blockade of potassium tail current by standard patch clamp analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of N-terminal 6-histine tagged Bacillus anthracis LF 263-C terminal catalytic domain using MCA-KKVYPYPME-Dap(Dnp)-NH2 as substrate after 4...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair