TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of JNK2 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of JNK3alpha-1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of human ROCK2 using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK peptide substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute
Curated by ChEMBL
Translational Research Institute
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research
Curated by ChEMBL
Johnson Matthey Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair