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Found 75 with Last Name = 'hesek' and Initial = 'd'
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82122(Vinylsulfone, 7)
Affinity DataKi:  0.530nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  5nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  6nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  6nMAssay Description:Inhibition of recombinant human MMP2 expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  13.9nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50459505(CHEMBL4215451)
Affinity DataKi:  19nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  23nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  28nMAssay Description:Inhibition of recombinant human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  37nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50459506(CHEMBL4214929)
Affinity DataKi:  37nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388911(CHEMBL2063270)
Affinity DataKi:  44nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50459506(CHEMBL4214929)
Affinity DataKi:  53nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388911(CHEMBL2063270)
Affinity DataKi:  61nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  64nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388912(CHEMBL2063273)
Affinity DataKi:  78nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  85nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  90nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388917(CHEMBL2063277)
Affinity DataKi:  110nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50459505(CHEMBL4215451)
Affinity DataKi:  119nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  120nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50459505(CHEMBL4215451)
Affinity DataKi:  127nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388916(CHEMBL2063276)
Affinity DataKi:  140nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  145nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  150nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388916(CHEMBL2063276)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  160nMAssay Description:Inhibition of recombinant human MMP9 expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388916(CHEMBL2063276)
Affinity DataKi:  180nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50459506(CHEMBL4214929)
Affinity DataKi:  190nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388910(CHEMBL2063271)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388912(CHEMBL2063273)
Affinity DataKi:  215nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388915(CHEMBL2063275)
Affinity DataKi:  280nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388913(CHEMBL2063272)
Affinity DataKi:  290nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388915(CHEMBL2063275)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase(Pseudomonas aeruginosa)
TBA

Curated by ChEMBL
LigandPNGBDBM50386412(CHEMBL2047302)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa PAO1 NagZ using PNP-GlcNAc as substrate assessed as release of 4-nitrophenolate ion after 4 mins by ...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  320nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388912(CHEMBL2063273)
Affinity DataKi:  390nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388910(CHEMBL2063271)
Affinity DataKi:  450nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388915(CHEMBL2063275)
Affinity DataKi:  470nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  575nMAssay Description:Competitive inhibition of human MMP3 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388911(CHEMBL2063270)
Affinity DataKi:  580nMAssay Description:Competitive inhibition of human MMP14 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  600nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM50388913(CHEMBL2063272)
Affinity DataKi:  600nMAssay Description:Competitive inhibition of human MMP2 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388917(CHEMBL2063277)
Affinity DataKi:  930nMAssay Description:Competitive inhibition of human MMP9 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82121(Gama, gama-dimethyl derivative, 6)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Notre Dame

LigandPNGBDBM82119(Sulfoxide, 4)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  2.10E+3nMAssay Description:Non-competitive inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50459506(CHEMBL4214929)
Affinity DataKi:  2.10E+3nMAssay Description:Non-competitive inhibition of human recombinant MMP8 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  2.20E+3nMAssay Description:Competitive inhibition of human MMP3 using fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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