Affinity DataKi: 0.0251nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Steady state and transient kinetics to a freely reversible, non-covalently bound, human recombinant Phospholipase A2 (rhLp-PLA2) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0316nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0398nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0631nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nM ΔG°: -57.1kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nM ΔG°: -56.3kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2More data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -54.9kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nM ΔG°: -51.0kJ/molepH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.98nMAssay Description:Antagonist activity at human oxytocin receptor assessed as inhibition of oxytocin binding by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Binding affinity to recombinant oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -46.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human oxytocin receptor assessed as inhibition of oxytocin binding by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to human oxytocin receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Antagonist activity at human oxytocin receptor assessed as inhibition of oxytocin binding by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at human oxytocin receptor assessed as inhibition of oxytocin binding by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 31.6nMAssay Description:Antagonist activity at human oxytocin receptor assessed as inhibition of oxytocin binding by FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Binding affinity to recombinant oxytocin receptorMore data for this Ligand-Target Pair