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Found 80 with Last Name = 'higgins' and Initial = 'c'
TargetBile salt export pump(Homo sapiens (Human))
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50375590(CHEMBL1552)
Affinity DataKi:  7.00E+3nMAssay Description:TP_TRANSPORTER: competitive inhibition of Taurocholate uptake in membrane vesicles prepared from High Five cells infected with the ABCB11 baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataKi:  9.50E+3nMAssay Description:TP_TRANSPORTER: inhibition of Taurochenodeoxycholate uptake(CsA 30uM, 30 % of control) in membrane vesicles prepared from High Five cells infected wi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50375589(CHEMBL411070)
Affinity DataKi:  1.10E+4nMAssay Description:TP_TRANSPORTER: competitive inhibition of Taurocholate uptake in membrane vesicles prepared from High Five cells infected with the ABCB11 baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataKi:  2.75E+4nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake(Glibenclamide 30uM, 50 % of control) in membrane vesicles prepared from High Five cells infected wi...More data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50375595(CHEMBL185878 | Taurochenodeoxycholate)
Affinity DataKi:  2.80E+4nMAssay Description:TP_TRANSPORTER: competitive inhibition of Taurocholate uptake in membrane vesicles prepared from High Five cells infected with the ABCB11 baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataKi:  3.10E+4nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake(Rifampicin SV 30uM, 50 % of control) in membrane vesicles prepared from High Five cells infected wi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015362(CHEMBL3264590)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015361(CHEMBL3264589)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015348(CHEMBL3264578)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499753(CHEMBL3741471)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499733(CHEMBL3740378)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499738(CHEMBL3740153)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015363(CHEMBL3264591)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015365(CHEMBL3264593)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015353(CHEMBL3264583)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015351(CHEMBL3264581)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499736(CHEMBL3740601)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015359(CHEMBL3264587)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015339(CHEMBL3264272)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499745(CHEMBL3741267)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015341(CHEMBL3264274)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015350(CHEMBL3264580)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499754(CHEMBL3740253)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499741(CHEMBL3739994)
Affinity DataIC50:  33nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499730(CHEMBL3740368)
Affinity DataIC50:  33nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499746(CHEMBL3739537)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015360(CHEMBL3264588)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015352(CHEMBL3264582)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499734(CHEMBL3741072)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499735(CHEMBL3740206)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015343(CHEMBL3264276)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015340(CHEMBL3264273)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499750(CHEMBL3741002)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015347(CHEMBL3264577)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015356(CHEMBL3264586)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499740(CHEMBL3740166)
Affinity DataIC50:  67nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499751(CHEMBL3742051)
Affinity DataIC50:  71nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499737(CHEMBL3741594)
Affinity DataIC50:  71nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499727(CHEMBL3740719)
Affinity DataIC50:  73nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499732(CHEMBL3742365)
Affinity DataIC50:  73nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015349(CHEMBL3264579)
Affinity DataIC50:  79nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015345(CHEMBL3264278)
Affinity DataIC50:  83nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499755(CHEMBL3741666)
Affinity DataIC50:  93nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015344(CHEMBL3264277)
Affinity DataIC50:  97nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015336(CHEMBL3264268)
Affinity DataIC50:  108nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50499752(CHEMBL3740086)
Affinity DataIC50:  121nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015354(CHEMBL3264584)
Affinity DataIC50:  124nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015338(CHEMBL3264271)
Affinity DataIC50:  138nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015334(CHEMBL3264594)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLegumain(Homo sapiens (Human))
Queen'S University Belfast

Curated by ChEMBL
LigandPNGBDBM50015342(CHEMBL3264275)
Affinity DataIC50:  169nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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