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Found 190 with Last Name = 'higuchi' and Initial = 's'
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578777(US11479550, Example 18-5(2))
Affinity DataKi:  120nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578749(US11479550, Example 3-9(2))
Affinity DataKi:  410nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578757(US11479550, Example 8-3(2))
Affinity DataKi:  1.50E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578759(US11479550, Example 8-13(2))
Affinity DataKi:  1.60E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataKi:  2.30E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578739(4-{4-[(1,1-dioxide-1,2-thiazolidin-2-yl)methyl]-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataIC50:  0.570nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578749(US11479550, Example 3-9(2))
Affinity DataIC50:  0.700nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578774(4-[2-({2-[3-methyl-6-(methylcarbamoyl)-1H-indol-1-...)
Affinity DataIC50:  0.790nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578746(US11479550, Example 3-3(2))
Affinity DataIC50:  0.900nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578743(US11479550, Example 2-6(2))
Affinity DataIC50:  1.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285498(4-[4-Cyano-2-({[(1R,2R)-6′-(methylcarbamoyl)...)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285464(4-{4-Cyano-2-[({2′R, 4S)-6-[(1-methyl 1H-pyr...)
Affinity DataIC50:  1.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578764(US11479550, Example 11-1(2))
Affinity DataIC50:  1.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578751(US11479550, Example 3-20(2))
Affinity DataIC50:  1.40nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578756(US11479550, Example 7-3(2))
Affinity DataIC50:  1.5nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578773(US11479550, Example 12-1(2))
Affinity DataIC50:  1.60nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285502(US10077247, Example 20-2)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578766(US11479550, Example 11-7(2))
Affinity DataIC50:  1.60nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578748(US11479550, Example 3-7(2))
Affinity DataIC50:  1.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578745(US11479550, Example 2-27(4))
Affinity DataIC50:  1.80nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataIC50:  1.90nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578768(US11479550, Example 11-11(2))
Affinity DataIC50:  2nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578747(US11479550, Example 3-5(2))
Affinity DataIC50:  2.10nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578762(US11479550, Example 9-5(2))
Affinity DataIC50:  2.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285487(4-[4-Cyano-2-({[(2′R,4S)-6-(1H-pyrazol-1-yl)...)
Affinity DataIC50:  2.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285036(US10077247, Example 1)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285470(4-[4-Cyano-2-({[(2′R,4S)-6-(3-pyridazinylcar...)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285480(4-[4-Cyano-2-({[(2′R,4S)-6-(propylcarbamoyl)...)
Affinity DataIC50:  2.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578752(US11479550, Example 4-1(2))
Affinity DataIC50:  2.5nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285500(4-{4-Cyano-2-[({(1R,2R)-6′-[(1-methyl-1H-pyr...)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285483(4-[4-Cyano-2-({[(2′R,4S)-6-(5-methyl-1,3,4-o...)
Affinity DataIC50:  2.70nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578765(US11479550, Example 11-3(2))
Affinity DataIC50:  2.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578754(US11479550, Example 6-5(1))
Affinity DataIC50:  2.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578753(US11479550, Example 4-8(2))
Affinity DataIC50:  2.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285484(US10077247, Example 5)
Affinity DataIC50:  2.80nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285482(4-[4-Cyano-2-({[(2′R,4S)-6-(ethylcarbamoyl)-...)
Affinity DataIC50:  3nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285499(4-{4-Cyano-2-[({(1R,2R)-6′-[(2-methoxyethyl)...)
Affinity DataIC50:  3nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578777(US11479550, Example 18-5(2))
Affinity DataIC50:  3.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285463(US10077247, Example 2-4)
Affinity DataIC50:  3.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578741(4-{4-[(4-chloro-1H-pyrazol-1-yl)methyl]-2-({2-[3-m...)
Affinity DataIC50:  3.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578755(US11479550, Example 7-1(2))
Affinity DataIC50:  3.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578758(US11479550, Example 8-9(2))
Affinity DataIC50:  3.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285478(4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-5-ylc...)
Affinity DataIC50:  3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285474(4-[4-Cyano-2-({[(2′R,4S)-6-(1,2-oxazol-3-ylc...)
Affinity DataIC50:  3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285476(US10077247, Example 2-39)
Affinity DataIC50:  3.40nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285462(US10077247, Example 2-3)
Affinity DataIC50:  3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285495(4-[4-Cyano-2-({[(2′R,4S)-6-(1-methyl-1H-1,2,...)
Affinity DataIC50:  3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285489(4-[4-Cyano-2-({[(2′R,4S)-6-(6-methoxy-3-pyri...)
Affinity DataIC50:  3.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM285479(4-{4-Cyano-2-[({(2′R,4S)-6-[(1-methyl-1H-pyr...)
Affinity DataIC50:  3.60nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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