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Found 113 with Last Name = 'hinsberger' and Initial = 's'
TargetElastase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50614323(CHEMBL4754924)
Affinity DataKi:  41nMAssay Description:Inhibition of Pseudomonas aeruginosa LasB elastase using aminobenzoyl-Ala-Gly-Leu-Ala-p-nitro-benzyl-amide as substrate b microtiter-based fluorimetr...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetElastase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataKi:  57nMAssay Description:Inhibition of Pseudomonas aeruginosa LasB elastase using aminobenzoyl-Ala-Gly-Leu-Ala-p-nitro-benzyl-amide as substrate b microtiter-based fluorimetr...More data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)TBA
LigandPNGBDBM113772(2-(4-Fluorophenyl)-2-(6-(trifluoromethyl)pyridin-2...)
Affinity DataKi:  190nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa ATCC 15692 pvdQMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331002(CHEMBL1277801 | [5-(3-Chloro-4-hydroxyphenyl)-2-th...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330998((5-(2-fluoro-3-hydroxyphenyl)thiophen-2-yl)(3-hydr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human cytosolic 17beta-HSD1 in cell-free system using [2,4,6,7-3H]E1 as substrate after 10 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331001((5-(4-hydroxy-3-(trifluoromethyl)phenyl)thiophen-2...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331000(CHEMBL1277709 | [5-(3-Fluoro-4-hydroxyphenyl)-2-th...)
Affinity DataIC50:  17nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using [2,4,6,7-3H]-estrone as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330994((4-fluoro-3-hydroxyphenyl)(5-(3-hydroxyphenyl)thio...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330992((3-hydroxyphenyl)(5-(2-hydroxyphenyl)thiophen-2-yl...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330998((5-(2-fluoro-3-hydroxyphenyl)thiophen-2-yl)(3-hydr...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331000(CHEMBL1277709 | [5-(3-Fluoro-4-hydroxyphenyl)-2-th...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)TBA
LigandPNGBDBM50257750(CHEMBL494325 | N-allyl-6-bromoquinazolin-4-amine |...)
Affinity DataIC50: <20nMAssay Description:Inhibition of Pseudomonas aeruginosa ATCC 15692 pvdQ incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcyl-homoserine lactone acylase PvdQ(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)TBA
LigandPNGBDBM113770(NS2028 (1))
Affinity DataIC50: <20nMAssay Description:Inhibition of Pseudomonas aeruginosa ATCC 15692 pvdQ incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331005(CHEMBL1277884 | [5-(3-Ethyl-4-hydroxyphenyl)-2-thi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330993((4-fluoro-3-hydroxyphenyl)(5-(4-hydroxyphenyl)thio...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330988((3-hydroxyphenyl)(5-(3-hydroxyphenyl)thiophen-2-yl...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360228(CHEMBL1928181)
Affinity DataIC50:  24nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  27nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using [2,4,6,7-3H]-estrone as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330997((5-(4-fluoro-3-hydroxyphenyl)thiophen-2-yl)(3-hydr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330991((3-hydroxyphenyl)(5-(4-hydroxyphenyl)thiophen-2-yl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using [2,4,6,7-3H]-estrone as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360229(CHEMBL1928182)
Affinity DataIC50:  31nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330991((3-hydroxyphenyl)(5-(4-hydroxyphenyl)thiophen-2-yl...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360227(CHEMBL1928180)
Affinity DataIC50:  34nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331006(CHEMBL1277885 | [2-(4-Hydroxy-3-methylphenyl)-1,3-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330994((4-fluoro-3-hydroxyphenyl)(5-(3-hydroxyphenyl)thio...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360228(CHEMBL1928181)
Affinity DataIC50:  53nMAssay Description:Inhibition of human cytosolic 17beta-HSD1 in cell-free system using [2,4,6,7-3H]E1 as substrate after 10 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330997((5-(4-fluoro-3-hydroxyphenyl)thiophen-2-yl)(3-hydr...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330993((4-fluoro-3-hydroxyphenyl)(5-(4-hydroxyphenyl)thio...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331003((5-(3,4-dihydroxyphenyl)thiophen-2-yl)(3-hydroxyph...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330992((3-hydroxyphenyl)(5-(2-hydroxyphenyl)thiophen-2-yl...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331001((5-(4-hydroxy-3-(trifluoromethyl)phenyl)thiophen-2...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360232(CHEMBL1928186)
Affinity DataIC50:  101nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331006(CHEMBL1277885 | [2-(4-Hydroxy-3-methylphenyl)-1,3-...)
Affinity DataIC50:  107nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using [2,4,6,7-3H]-estrone as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331004((5-(4-hydroxy-3-methoxyphenyl)thiophen-2-yl)(3-hyd...)
Affinity DataIC50:  108nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330988((3-hydroxyphenyl)(5-(3-hydroxyphenyl)thiophen-2-yl...)
Affinity DataIC50:  109nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331002(CHEMBL1277801 | [5-(3-Chloro-4-hydroxyphenyl)-2-th...)
Affinity DataIC50:  126nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using [2,4,6,7-3H]-estrone as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360223(CHEMBL1928176)
Affinity DataIC50:  132nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)TBA
LigandPNGBDBM50614327(CHEMBL5286977)
Affinity DataIC50:  140nMAssay Description:Inhibition of Pseudomonas aeruginosa LecBMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360233(CHEMBL1928187)
Affinity DataIC50:  153nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360226(CHEMBL1928179)
Affinity DataIC50:  153nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360229(CHEMBL1928182)
Affinity DataIC50:  159nMAssay Description:Inhibition of human cytosolic 17beta-HSD1 in cell-free system using [2,4,6,7-3H]E1 as substrate after 10 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360225(CHEMBL1928178)
Affinity DataIC50:  176nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331007((5-(4-hydroxy-3-methylphenyl)thiophen-3-yl)(3-hydr...)
Affinity DataIC50:  199nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330996((5-(3-hydroxy-4-methylphenyl)thiophen-2-yl)(3-hydr...)
Affinity DataIC50:  207nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360230(CHEMBL1928184)
Affinity DataIC50:  220nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330995((3-hydroxy-4-nitrophenyl)(5-(3-hydroxyphenyl)thiop...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50331002(CHEMBL1277801 | [5-(3-Chloro-4-hydroxyphenyl)-2-th...)
Affinity DataIC50:  246nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360231(CHEMBL1928185)
Affinity DataIC50:  260nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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