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Found 208 with Last Name = 'hoerer' and Initial = 's'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329791((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataIC50:  1nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285776(CHEMBL4172309)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285750(CHEMBL4173049)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285745(CHEMBL4162641)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285744(CHEMBL4168498)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285777(CHEMBL4165749)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human ATXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285748(CHEMBL4173341)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285774(CHEMBL4169550)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329795((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataIC50:  3nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329793((Z)-3-((4-(N-(2-(dimethylamino)ethyl)acetamido)phe...)
Affinity DataIC50:  3nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50187693(CHEMBL3186509)
Affinity DataIC50:  3nMAssay Description:Inhibition of human full length ATX expressed in HEK cells using FS-3 as substrate incubated for 15 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285751(CHEMBL4169912)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285777(CHEMBL4165749)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285774(CHEMBL4169550)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285773(CHEMBL4170966)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285743(CHEMBL4169136)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285775(CHEMBL4159308)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329792((Z)-3-((4-(N-(2-(dimethylamino)ethyl)methylsulfona...)
Affinity DataIC50:  7nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329798((Z)-N-ethyl-N-methyl-3-((4-(N-methyl-2-(4-methylpi...)
Affinity DataIC50:  7nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285748(CHEMBL4173341)
Affinity DataIC50:  7nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329794((Z)-3-((4-(N-(2-(dimethylamino)ethyl)acetamido)phe...)
Affinity DataIC50:  8nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272797(CHEMBL4126886)
Affinity DataIC50:  9nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329797((Z)-N-ethyl-3-((4-(N-methyl-2-(4-methylpiperazin-1...)
Affinity DataIC50:  9nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329796((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataIC50:  9nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285778(CHEMBL4164935)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285742(CHEMBL4163050)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329814((Z)-N-ethyl-3-((4-(N-methyl-2-(4-methylpiperazin-1...)
Affinity DataIC50:  15nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329813((Z)-3-((4-(N-(3-(dimethylamino)propyl)acetamido)ph...)
Affinity DataIC50:  17nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285750(CHEMBL4173049)
Affinity DataIC50:  18nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329799((Z)-3-((4-((dimethylamino)methyl)phenylamino)(phen...)
Affinity DataIC50:  19nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272769(CHEMBL4127386)
Affinity DataIC50:  20nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329784((Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)...)
Affinity DataIC50:  24nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329801((Z)-3-((4-(2-(dimethylamino)-N-methylacetamido)phe...)
Affinity DataIC50:  29nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285777(CHEMBL4165749)
Affinity DataIC50:  29nMAssay Description:Inhibition of ATX in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272768(CHEMBL4129994)
Affinity DataIC50:  30nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329802((Z)-N-ethyl-3-((4-((ethylamino)methyl)phenylamino)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279165(CHEMBL1203982 | CHEMBL497724)
Affinity DataIC50:  32nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285776(CHEMBL4172309)
Affinity DataIC50:  33nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329803((Z)-3-((4-(2-(diethylamino)ethylcarbamoyl)phenylam...)
Affinity DataIC50:  33nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279164((3Z)-N-ETHYL-N-METHYL-2-OXO-3-(PHENYL{[4-(PIPERIDI...)
Affinity DataIC50:  34nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279163(CHEMBL1203981 | CHEMBL496861)
Affinity DataIC50:  35nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329800((Z)-3-((4-(2-(dimethylamino)-N-methylacetamido)phe...)
Affinity DataIC50:  35nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272886(CHEMBL4127978)
Affinity DataIC50:  40nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272887(CHEMBL4126888)
Affinity DataIC50:  40nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272771(CHEMBL4128038)
Affinity DataIC50:  40nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329805((Z)-3-((4-(2-(dimethylamino)ethyl)phenylamino)(phe...)
Affinity DataIC50:  47nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285775(CHEMBL4159308)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50272888(CHEMBL4130152)
Affinity DataIC50:  50nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329816((Z)-3-((4-(2-(dimethylamino)-N-methylacetamido)phe...)
Affinity DataIC50:  52nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285751(CHEMBL4169912)
Affinity DataIC50:  56nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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