Affinity DataIC50: 1nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human ATXMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human full length ATX expressed in HEK cells using FS-3 as substrate incubated for 15 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of ATX in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Modulation of gamma secretase in human H4 cells expressing human wild type APP assessed as inhibition of amyloid beta 42 production after 22 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Boehringer Ingelheim Pharma
Curated by ChEMBL
Boehringer Ingelheim Pharma
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair