Compile Data Set for Download or QSAR
maximum 50k data
Found 286 with Last Name = 'hofmann' and Initial = 'h'
LigandPNGBDBM50180775(CHEMBL386763 | FV-Aib-TDVGPFAF | [Aib29,Asp31,Pro3...)
Affinity DataKi:  0.00200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50180778(CHEMBL2371891 | FV-Hyp-TDVGPFAF)
Affinity DataKi:  0.00600nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50180781(CHEMBL2371890 | FV-Tic-TDVGPFAF)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50062162(CHEMBL264010 | FVPTDVGPFAF)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50180777(CHEMBL427759 | FV((1R,2R,3R)-beta-aminocyclopropan...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50180776(CHEMBL2371892 | FVPTDVG-Tic-FAF-Tic)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50180776(CHEMBL2371892 | FVPTDVG-Tic-FAF-Tic)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116042(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128678(CHEMBL310855 | N-(1-Carbamoyl-2-phenyl-ethyl)-2-(2...)
Affinity DataKi:  8.40nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50180783(CHEMBL385986 | FVATDVGPFAF)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092301(1-(Benzo[b]thiophene-2-carbonyl)-piperidine-4-carb...)
Affinity DataKi:  9nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116048(CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128679(CHEMBL77784 | N-(1-Carbamoyl-pentyl)-2-[2-(4-dimet...)
Affinity DataKi:  13.3nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50062214(CHEMBL406459 | FVPTDVGAFAF)
Affinity DataKi:  14nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50062162(CHEMBL264010 | FVPTDVGPFAF)
Affinity DataKi:  14nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128680(CHEMBL80903 | N-(1-Benzyl-2-oxo-ethyl)-2-(2-naphth...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataKi:  15nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataKi:  15.5nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataKi:  18nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128681(CHEMBL80933 | N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-...)
Affinity DataKi:  18.3nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50073850((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...)
Affinity DataKi:  25nMAssay Description:Inhibition of human Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128679(CHEMBL77784 | N-(1-Carbamoyl-pentyl)-2-[2-(4-dimet...)
Affinity DataKi:  27nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128682(CHEMBL80605 | N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-...)
Affinity DataKi:  27nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092297(1-(Naphthalene-2-carbonyl)-piperidine-4-carboxylic...)
Affinity DataKi:  30nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  46nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128682(CHEMBL80605 | N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-...)
Affinity DataKi:  62nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50062214(CHEMBL406459 | FVPTDVGAFAF)
Affinity DataKi:  77nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128681(CHEMBL80933 | N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-...)
Affinity DataKi:  83nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50128678(CHEMBL310855 | N-(1-Carbamoyl-2-phenyl-ethyl)-2-(2...)
Affinity DataKi:  99nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  100nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50112839(CHEMBL26631 | N-(1-Benzyl-2-oxo-ethyl)-2-styryl-be...)
Affinity DataKi:  140nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092294(1-(Quinoline-6-carbonyl)-piperidine-4-carboxylic a...)
Affinity DataKi:  160nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116046(CHEMBL12465 | [7-(3-Aminomethyl-pyrrol-1-yl)-6-nit...)
Affinity DataKi:  230nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116044(CHEMBL416685 | {6-Nitro-2,3-dioxo-7-[3-(4-phenyl-p...)
Affinity DataKi:  230nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116047((6-Nitro-2,3-dioxo-7-{3-[(3-phenyl-propylamino)-me...)
Affinity DataKi:  320nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116041(CHEMBL303415 | [6-Nitro-2,3-dioxo-7-(3-piperidin-1...)
Affinity DataKi:  330nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116045(3-(7-{3-[(Benzyl-methyl-amino)-methyl]-pyrrol-1-yl...)
Affinity DataKi:  430nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092298(1-(Naphthalene-2-sulfonyl)-piperidine-4-carboxylic...)
Affinity DataKi:  450nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092300(1-[(E)-(3-Phenyl-acryloyl)]-piperidine-4-carboxyli...)
Affinity DataKi:  460nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116049((6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-qu...)
Affinity DataKi:  530nMAssay Description:Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116044(CHEMBL416685 | {6-Nitro-2,3-dioxo-7-[3-(4-phenyl-p...)
Affinity DataKi:  530nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092295(1-Benzoyl-piperidine-4-carboxylic acid (1-benzyl-2...)
Affinity DataKi:  560nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116040((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Affinity DataKi:  610nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092299(1-(Quinoline-3-carbonyl)-piperidine-4-carboxylic a...)
Affinity DataKi:  670nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116042(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Affinity DataKi:  680nMAssay Description:Binding affinity towards cloned human GluR7 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092302(1-(Naphthalene-2-sulfonyl)-piperidine-4-carboxylic...)
Affinity DataKi:  810nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50092305(1-(Naphthalene-2-carbonyl)-piperidine-4-carboxylic...)
Affinity DataKi:  960nMAssay Description:Inhibition of Suc-Leu-Tyr-AMC binding to human mu-calpain from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50112838(CHEMBL281874 | N-(1-Benzyl-2-oxo-ethyl)-benzamide)
Affinity DataKi:  1.08E+3nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50116043(3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-3,4-dihydro-2H-...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for human GluR6 expressed in HEK-293 cells using [3]H-kainateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50288367(3-(2,3-Dioxo-7-pyrrol-1-yl-6-trifluoromethyl-3,4-d...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was tested for binding affinity against glycine site of NMDA receptor using [3H]-glycine as a radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
Displayed 1 to 50 (of 286 total ) | Next | Last >>
Jump to: