Target5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2(Homo sapiens (Human))
Vanderbilt University
Vanderbilt University
Affinity DataIC50: <1nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.29nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.14nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human ALK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein 4(Mus musculus)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25.1nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
Affinity DataIC50: 25.1nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26.7nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
Affinity DataIC50: 26.7nMAssay Description:Shown are the IC50s (concentrations causing 50% inhibition) of DM and the analogues for the in vitro kinase assays using the following purified human...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human ALK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair