BindingDB PrimarySearch_ki

Found 1034 with Last Name = 'hori' and Initial = 'a'

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)

Ki: 0.0210nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 60 mins by activity based 100 fold dilution assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50327046(1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin...)

Ki: 0.0240nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 60 mins by activity based 100 fold dilution assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50327046(1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin...)

Ki: 0.0440nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 60 mins by ligand displacement based enzyme-inhibitor dilution assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)

Ki: 0.120nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 60 mins by ligand displacement based enzyme-inhibitor dilution assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)

Ki: 1.70nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 10 mins by Global fit analysisMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)

Ki: 2.90nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 10 mins by Global fit analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50327046(1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin...)

Ki: 4.60nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 10 mins by Global fit analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)

Ki: 22nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 10 mins by Global fit analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50327046(1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin...)

Ki: 23nMAssay Description:Inhibition of human N-terminal His-tagged phosphorylated VEGFR2 in presence of ATP measured without preincubation by AlphaScreen analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208878(CHEMBL3883415)

Ki: 2.00E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50389606(CHEMBL2069625)

Ki: 2.50E+4nMAssay Description:Inhibition of human unphosphorylated N-terminal-His6 tagged VEGFR2 catalytic domain using 5-FAM-EEPLYWSFPAKKK-CONH2 as substrate after 60 mins by mob...More data for this Ligand-Target Pair

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3D Structure (crystal)

NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208780(CHEMBL3884180)

Ki: 5.50E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208778(CHEMBL3885397)

Ki: 6.50E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208802(CHEMBL3885465)

Ki: 8.00E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208739(CHEMBL3885207)

Ki: 8.00E+4nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208736(CHEMBL3883373)

Ki: 1.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208741(CHEMBL3883614)

Ki: 1.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208740(CHEMBL3885345)

Ki: 1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208745(CHEMBL3884239)

Ki: 1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208904(CHEMBL3884876)

Ki: 1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208805(CHEMBL3883397)

Ki: 1.40E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208743(CHEMBL3884081)

Ki: 1.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208779(CHEMBL3884775)

Ki: 1.60E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208737(CHEMBL3884746)

Ki: 1.60E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208795(CHEMBL3885356)

Ki: 1.80E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208735(CHEMBL3884857)

Ki: 2.00E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208774(CHEMBL3885310)

Ki: 2.10E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208874(CHEMBL3883624)

Ki: 2.20E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208781(CHEMBL3883763)

Ki: 2.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208773(CHEMBL3884901)

Ki: 2.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208775(CHEMBL3884119)

Ki: 3.00E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208742(CHEMBL3884982)

Ki: 3.30E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208734(CHEMBL3883980)

Ki: 3.35E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208738(CHEMBL3885227)

Ki: 3.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208744(CHEMBL3885137)

Ki: 3.50E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208776(CHEMBL3883970)

Ki: 4.25E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208777(CHEMBL3883775)

Ki: 5.25E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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NAD kinase(Homo sapiens (Human))
France Cnrs

Curated by ChEMBL

PNG

BDBM50208905(CHEMBL3884652)

Ki: 7.75E+5nMAssay Description:Inhibition of human NADK expressed in Escherichia coli BL21(DE3) assessed as reduction in NADP production using NAD as substrate by glucose-6-phospha...More data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50327046(1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin...)

IC50: 0.0330nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 preincubated for 120 mins in presence of ATP by AlphaScreen analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50399537(CHEMBL2180604)

IC50: 0.0930nMAssay Description:Inhibition of VEGFR2 (unknown origin) using biotinylated poly(Glu:Tyr) as substrate after 60 mins by AlphaScreen assay in presence of 1000 uM of ATPMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)

IC50: 0.160nMAssay Description:Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 preincubated for 120 mins in presence of ATP by AlphaScreen analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451372(CHEMBL4217405)

IC50: 0.170nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50432398(CHEMBL2348996)

IC50: 0.190nMAssay Description:Inhibition of VEGFR2 (unknown origin) using biotinylated poly(Glu:Tyr) as substrate after 60 mins by AlphaScreen assay in presence of 1000 uM of ATPMore data for this Ligand-Target Pair

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3D Structure (crystal)

Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451394(CHEMBL4205606)

IC50: 0.200nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

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Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451373(CHEMBL4206924)

IC50: 0.200nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

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Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451392(CHEMBL4214725)

IC50: 0.200nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

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Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451391(CHEMBL4212088)

IC50: 0.200nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

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Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451384(CHEMBL4210064)

IC50: 0.240nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451385(CHEMBL4205969)

IC50: 0.310nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

Somatostatin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL

PNG

BDBM50451382(CHEMBL4205696)

IC50: 0.530nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed

Displayed 1 to 50 (of 1034 total ) | Next | Last >>

Filter my 1034 hits

Targets 82▿
- Beta-secretase 1 237
- Tyrosine-protein kinase JAK3 151
- Vascular endothelial growth factor receptor 2 128
- Tyrosine-protein kinase Lck 62
- Rho-associated protein kinase 2 61
- Nuclear receptor ROR-gamma 58
- Focal adhesion kinase 1 51
- NAD kinase 37
- Fibroblast growth factor receptor 1 30
- Hepatocyte growth factor receptor 25
- Somatostatin receptor type 2 23
- Tyrosine-protein kinase JAK2 10
- Serine/threonine-protein kinase B-raf 10
- Platelet-derived growth factor receptor beta 9
- Aurora kinase A 8
- Protein-tyrosine kinase 2-beta 7
- Cytochrome P450 3A4 7
- Cytochrome P450 2D6 6
- Serine/threonine-protein kinase MRCK alpha 4
- Mitogen-activated protein kinase 10 4
- Rho-associated protein kinase 1 4
- Proto-oncogene tyrosine-protein kinase Src 4
- Receptor tyrosine-protein kinase erbB-2 4
- Platelet-derived growth factor receptor alpha 4
- Dual specificity mitogen-activated protein kinase kinase 1 3
- Insulin-like growth factor 1 receptor 3
- Mitogen-activated protein kinase 14 3
- Aurora kinase B 3
- Insulin receptor 3
- RAC-alpha serine/threonine-protein kinase 3
- Vascular endothelial growth factor receptor 1 3
- Mitogen-activated protein kinase kinase kinase 9 2
- Tyrosine-protein kinase Fyn 2
- Tyrosine-protein kinase JAK1/JAK2 2
- Tyrosine-protein kinase JAK1 2
- Angiopoietin-1 receptor 2
- Mitogen-activated protein kinase kinase kinase kinase 2 2
- Serine/threonine-protein kinase Chk2 2
- Mast/stem cell growth factor receptor Kit 2
- Somatostatin receptor type 5 2
- Cytochrome P450 1A2 2
- Mitogen-activated protein kinase kinase kinase kinase 4 2
- Tyrosine-protein kinase Yes 2
- Cytochrome P450 2C9 2
- Non-receptor tyrosine-protein kinase TYK2 2
- Myosin light chain kinase, smooth muscle 2
- Cytochrome P450 2C19 2
- Tyrosine-protein kinase Fgr 2
- Glycogen synthase kinase-3 beta 2
- Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK2 1
- Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1 1
- Mitogen-activated protein kinase 3 1
- Retinoic acid receptor alpha 1
- Steroidogenic factor 1 1
- Beta-secretase 2 1
- Nuclear receptor ROR-beta 1
- Vitamin D3 receptor 1
- Progesterone receptor 1
- Retinoic acid receptor beta 1
- Potassium voltage-gated channel subfamily H member 2 1
- Epidermal growth factor receptor 1
- Somatostatin receptor type 3 1
- Somatostatin receptor type 4 1
- Somatostatin receptor type 1 1
- Glucocorticoid receptor 1
- Fibroblast growth factor receptor 4 1
- Cathepsin D 1
- Oxysterols receptor LXR-alpha 1
- Vascular endothelial growth factor receptor 3 1
- Cytochrome P450 2A6 1
- Fibroblast growth factor receptor 3 1
- Peroxisome proliferator-activated receptor gamma 1
- Cathepsin E 1
- Retinoic acid receptor RXR-alpha 1
- Peroxisome proliferator-activated receptor delta 1
- Peroxisome proliferator-activated receptor alpha 1
- JAK3/JAK1 1
- Macrophage colony-stimulating factor 1 receptor 1
- Protein kinase C theta type 1
- Bile acid receptor 1
- Proto-oncogene tyrosine-protein kinase receptor Ret 1
- Nuclear receptor ROR-alpha 1
- ...
Publications 22▿
- J Med Chem 63: 7163-7185 (2020) 141
- US Patent US8609647 (2013) 91
- ACS Med Chem Lett 7: 23-7 (2016) 82
- J Med Chem 53: 5727-37 (2010) 73
- US Patent US8546380 (2013) 61
- US Patent US8633188 (2014) 60
- Bioorg Med Chem 18: 7150-63 (2010) 54
- Eur J Med Chem 61: 49-60 (2013) 46
- Bioorg Med Chem Lett 23: 1779-85 (2013) 44
- Bioorg Med Chem 18: 7260-73 (2010) 44
- Bioorg Med Chem 21: 2333-45 (2013) 41
- Eur J Med Chem 124: 1041-1056 (2016) 37
- J Med Chem 64: 1873-1888 (2021) 37
- US Patent US8637504 (2014) 37
- US Patent US9650371 (2017) 37
- Bioorg Med Chem 25: 5995-6006 (2017) 28
- Bioorg Med Chem 19: 5342-51 (2011) 26
- Bioorg Med Chem 21: 7686-98 (2013) 24
- Bioorg Med Chem 21: 4714-29 (2013) 23
- Bioorg Med Chem 20: 7051-8 (2012) 22
- US Patent US8999980 (2015) 19
- ACS Med Chem Lett 3: 342-346 (2012) 7
Institutions 8▿
- Takeda Pharmaceutical 352
- Japan Tobacco 232
- Shionogi 214
- Central Pharmaceutical Research Institute 82
- The Scripps Research Institute 73
- Janssen Research & Development 37
- France Cnrs 37
- TBA 7
Affinity: 0.021 to 7.8E+5 nM▿
- Ki 38
- IC50 923
- Kd 1
- EC50 72
- Affinity ≤ nM
Xtal structures: 19
Docked structures: 0
Catalog Cmpds: 17