Compile Data Set for Download or QSAR
maximum 50k data
Found 220 with Last Name = 'housley' and Initial = 't'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215791(2-((2-acetamidopyridin-4-yl)methylamino)-N-(2,2-di...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215766(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50091927(1-(2,6-Dichloro-phenyl)-1-(4'-fluoro-6-hydroxymeth...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 expressed in E. coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215793(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215761(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215774(CHEMBL246424 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215788(CHEMBL399534 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215770(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215758(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215759(CHEMBL247423 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50114250(1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-(4-pyr...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human epidermal growth factor receptor-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215791(2-((2-acetamidopyridin-4-yl)methylamino)-N-(2,2-di...)
Affinity DataIC50:  5nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215773(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215761(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215775(1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095409(5-tert-Butyl-3-[3-(2,3-dichloro-phenyl)-ureido]-1H...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215770(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  7nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215789(1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215782(CHEMBL398052 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215798(CHEMBL395700 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215777(4-((4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50091931(1-[5-tert-Butyl-2-(3-nitro-phenyl)-2H-pyrazol-3-yl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215787(4-((5-((2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215776(CHEMBL247591 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215768(1-methyl-3-(5-((1-methyl-4-((2,2,3,3-tetrafluoro-2...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50095390(5-tert-Butyl-3-(3-naphthalen-1-yl-ureido)-1H-pyrro...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215772(CHEMBL248860 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50091935(1-[2-(3-Amino-phenyl)-5-tert-butyl-2H-pyrazol-3-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50114245(1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-[4-(py...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215763(1-methyl-3-(5-((1-methyl-4-((4-(trifluoromethylthi...)
Affinity DataIC50:  15nMAssay Description:Inhibition of pAktMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215771(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215795(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215763(1-methyl-3-(5-((1-methyl-4-((4-(trifluoromethylthi...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215784(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215781(2-(pyridin-4-ylmethylamino)-N-(2,2,3,3-tetrafluoro...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215785(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 expressed in E. coli.More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215790(2-((2-(3-(1H-imidazol-1-yl)propylamino)pyridin-4-y...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of mitogen-activated protein kinase p38 alpha 2 derived from E. coliMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215799(2-((2-(2-(1H-imidazol-5-yl)ethylamino)pyridin-4-yl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215761(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  24nMAssay Description:Inhibition of pAktMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215775(1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Affinity DataIC50:  24nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215792(4-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215794(CHEMBL246423 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215765(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215774(CHEMBL246424 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215767(2-((2-carbamothioylpyridin-4-yl)methylamino)-N-(2,...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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